Protein: YIPF5
Protein YIPF5 (Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 5) (Smooth muscle cell-associated protein 5) (SMAP-5) (YIP1 family member 5) (YPT-interacting protein 1 A)

Gene: YIPF5
Organism: Homo sapiens
Interactions: 138
UniProt ID: Q969M3

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005794 - Golgi apparatus
GO:0005802 - trans-Golgi network

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

325577

YIF1A
Protein YIF1A

4

5

High-throughput

0.698

High

1380495

VAPA
Vesicle-associated membrane protein-associated protein A

2

1

High-throughput

0.628

High

1203384

YIF1B
Protein YIF1B

2

5

High-throughput

0.611

High

1380485

UN93B
Protein unc-93 homolog B1

2

1

High-throughput

0.611

High

1380480

ESYT1
Extended synaptotagmin-1

2

0

High-throughput

0.585

High

141851

ACKR2
Atypical chemokine receptor 2

1

3

High-throughput

0.536

High

257657

PRAF2
PRA1 family protein 2

1

1

High-throughput

0.536

High

338524

SC24B
Protein transport protein Sec24B

1

3

High-throughput

0.536

High

349519

TSN15
Tetraspanin-15

1

1

High-throughput

0.536

High

360064

NB5R3
NADH-cytochrome b5 reductase 3

1

1

High-throughput

0.536

High

420646

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

3

High-throughput

0.536

High

477444

CD63
CD63 antigen

1

1

High-throughput

0.536

High

766748

PHB1
Prohibitin 1

1

3

High-throughput

0.536

High

901460

RAB7A
Ras-related protein Rab-7a

1

8

High-throughput

0.536

High

956436

RAB2A
Ras-related protein Rab-2A

1

4

High-throughput

0.536

High

981338

RAB1A
Ras-related protein Rab-1A

1

5

High-throughput

0.536

High

1023377

AT2C1
Calcium-transporting ATPase type 2C member 1

1

3

High-throughput

0.536

High

1027118

REEP5
Receptor expression-enhancing protein 5

1

3

High-throughput

0.536

High

1041218

CAV1
Caveolin-1

1

1

High-throughput

0.536

High

1089996

LMAN2
Vesicular integral-membrane protein VIP36

1

1

High-throughput

0.536

High

1146595

TMED2
Transmembrane emp24 domain-containing protein 2

1

5

High-throughput

0.536

High

1148923

SC23A
Protein transport protein Sec23A

1

3

High-throughput

0.536

High

1199227

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

4

High-throughput

0.536

High

1239902

CAVN1
Caveolae-associated protein 1

1

1

High-throughput

0.536

High

1252869

MBOA1
Membrane-bound glycerophospholipid O-acyltransferase 1

1

2

High-throughput

0.536

High

1281260

TMED4
Transmembrane emp24 domain-containing protein 4

1

5

High-throughput

0.536

High

1291441

RETR3
Reticulophagy regulator 3

1

2

High-throughput

0.536

High

1337895

ZNT7
Zinc transporter 7

1

4

High-throughput

0.536

High

1350027

SPP2B
Signal peptide peptidase-like 2B

1

2

High-throughput

0.536

High

1356527

RAB2B
Ras-related protein Rab-2B

1

7

High-throughput

0.536

High

1380471

MBOA7
Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

1

2

High-throughput

0.536

High

1380483

RAB1B
Ras-related protein Rab-1B

1

5

High-throughput

0.536

High

1380484

LMA2L
VIP36-like protein

1

1

High-throughput

0.536

High

1380490

RAB18
Ras-related protein Rab-18

1

7

High-throughput

0.536

High

1380492

SAR1A
Small COPII coat GTPase SAR1A

1

5

High-throughput

0.536

High

1380494

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.536

High

1380497

PRAF1
Prenylated Rab acceptor protein 1

1

2

High-throughput

0.536

High

1380498

TMCO1
Calcium load-activated calcium channel

1

1

High-throughput

0.536

High

1380501

TMED5
Transmembrane emp24 domain-containing protein 5

1

5

High-throughput

0.536

High

1380504

IR3IP
Immediate early response 3-interacting protein 1

1

2

High-throughput

0.536

High

458458

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.518

High

138261

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.513

High

161237

EI24
Etoposide-induced protein 2.4 homolog

1

0

High-throughput

0.513

High

184208

RER1
Protein RER1

1

0

High-throughput

0.513

High

328965

RTN3
Reticulon-3

1

0

High-throughput

0.513

High

857151

NSF
Vesicle-fusing ATPase

1

0

High-throughput

0.513

High

904047

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.513

High

1009865

NUCB2
Nucleobindin-2

1

0

High-throughput

0.513

High

1089153

TM115
Transmembrane protein 115

1

0

High-throughput

0.513

High

1133269

ARI5B
AT-rich interactive domain-containing protein 5B

1

0

High-throughput

0.513

High

1139358

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.513

High

1145645

RCN1
Reticulocalbin-1

1

0

High-throughput

0.513

High

1159322

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.513

High

1201658

SFT2C
Vesicle transport protein SFT2C

1

0

High-throughput

0.513

High

1292855

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.513

High

1310286

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1340947

MCFD2
Multiple coagulation factor deficiency protein 2

1

0

High-throughput

0.513

High

1358329

SCFD1
Sec1 family domain-containing protein 1

1

0

High-throughput

0.513

High

1380469

SC22A
Vesicle-trafficking protein SEC22a

1

0

High-throughput

0.513

High

1380473

PIGS
GPI-anchor transamidase component PIGS

1

0

High-throughput

0.513

High

1380475

MPP8
M-phase phosphoprotein 8

1

0

High-throughput

0.513

High

1380477

SOSB1
SOSS complex subunit B1

1

0

High-throughput

0.513

High

1380479

ERP44
Endoplasmic reticulum resident protein 44

1

0

High-throughput

0.513

High

1380481

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.513

High

1380486

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.513

High

1380503

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

1380506

CEPT1
Choline/ethanolaminephosphotransferase 1

1

0

High-throughput

0.513

High

166006

FFAR1
Free fatty acid receptor 1

1

11

High-throughput

0.489

High

182707

GP182
G-protein coupled receptor 182

1

3

High-throughput

0.489

High

231808

MFS11
UNC93-like protein MFSD11

1

1

High-throughput

0.489

High

351939

S1PR4
Sphingosine 1-phosphate receptor 4

1

6

High-throughput

0.489

High

443907

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

1

High-throughput

0.489

High

538653

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

1

High-throughput

0.489

High

680455

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

1

High-throughput

0.489

High

733036

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

3

High-throughput

0.489

High

820571

GPV
Platelet glycoprotein V

1

1

High-throughput

0.489

High

833850

P2RY2
P2Y purinoceptor 2

1

6

High-throughput

0.489

High

845096

EAA3
Excitatory amino acid transporter 3

1

3

High-throughput

0.489

High

900971

RAB5C
Ras-related protein Rab-5C

1

8

High-throughput

0.489

High

1142127

P2RY6
P2Y purinoceptor 6

1

7

High-throughput

0.489

High

1153295

AAAT
Neutral amino acid transporter B(0)

1

3

High-throughput

0.489

High

1205012

RABL3
Rab-like protein 3

1

10

High-throughput

0.489

High

1212278

TM63B
Mechanosensitive cation channel TMEM63B

1

2

High-throughput

0.489

High

1291854

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

8

High-throughput

0.489

High

1357244

S38A5
Sodium-coupled neutral amino acid transporter 5

1

1

High-throughput

0.489

High

1380041

CAVN3
Caveolae-associated protein 3

1

1

High-throughput

0.489

High

1380476

PHB2
Prohibitin-2

1

3

High-throughput

0.489

High

1380489

GPR35
G-protein coupled receptor 35

1

6

High-throughput

0.489

High

1380500

SC6A5
Sodium- and chloride-dependent glycine transporter 2

1

3

High-throughput

0.489

High

508386

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

282613

ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

Small-scale

0.479

High

414356

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

418330

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

581215

RAC2
Ras-related C3 botulinum toxin substrate 2

1

3

High-throughput

0.479

High

953603

RAC3
Ras-related C3 botulinum toxin substrate 3

1

3

High-throughput

0.479

High

988589

RAC1
Ras-related C3 botulinum toxin substrate 1

1

3

High-throughput

0.479

High

1015656

RHOG
Rho-related GTP-binding protein RhoG

1

3

High-throughput

0.479

High

1380499

SSRG
Translocon-associated protein subunit gamma

1

1

High-throughput

0.479

High

1380502

TMED7
Transmembrane emp24 domain-containing protein 7

1

5

High-throughput

0.479

High

831187

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

980098

H4
Histone H4

1

0

High-throughput

0.458

High

1178291

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1312569

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.458

High

1366961

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1380468

FAF2
FAS-associated factor 2

1

0

High-throughput

0.458

High

1380470

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1380472

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

1380474

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1380482

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

1380488

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1380491

ANLN
Anillin

1

0

High-throughput

0.458

High

1380496

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

91623

C9JA28
Translocon-associated protein subunit gamma

1

1

High-throughput

0.445

High

564168

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.445

High

1294143

TCAM2
TIR domain-containing adapter molecule 2

1

0

High-throughput

0.426

High

91723

C9JKI3
Caveolin

1

1

High-throughput

0.407

High

189988

MOT7
Monocarboxylate transporter 7

1

5

High-throughput

0.407

High

1380505

FLVC1
Choline/ethanolamine transporter FLVCR1

1

3

High-throughput

0.407

High

49746

TMM72
Transmembrane protein 72

1

0

High-throughput

0.279

Low

528494

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

0

High-throughput

0.279

Low

576128

CX6B1
Cytochrome c oxidase subunit 6B1

1

0

High-throughput

0.279

Low

617563

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

1

0

High-throughput

0.279

Low

683879

MOES
Moesin

1

0

High-throughput

0.279

Low

869934

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

0

High-throughput

0.279

Low

933042

SNAA
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.279

Low

1100703

STX3
Syntaxin-3

1

0

High-throughput

0.279

Low

1273264

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

0

High-throughput

0.279

Low

1280134

PTAR1
Protein prenyltransferase alpha subunit repeat-containing protein 1

1

0

High-throughput

0.279

Low

1327704

MACOI
Macoilin

1

0

High-throughput

0.279

Low

1350850

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1380478

TBA1C
Tubulin alpha-1C chain

1

0

High-throughput

0.279

Low

1380493

T161A
Transmembrane protein 161A

1

0

High-throughput

0.279

Low

125561

LEG9
Galectin-9

1

0

High-throughput

0.249

Low

941514

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.249

Low

970882

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

1162462

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

1380487

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

220616

AKA10
A-kinase anchor protein 10, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025