HitPredict

Interactor 1: S61A1 (P61619)
Protein transport protein Sec61 subunit alpha isoform 1 (Sec61 alpha-1)
Gene: SEC61A1

Interactor 2: DDR2 (Q16832)
Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)
Gene: DDR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 476 Hs			1 855
+	Hs
		384593 S61A1_HUMAN (1-476): 0: 717: 100.00		NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62
+	Hs
		609236 S61A1_HUMAN (1-476): 0: 717: 100.00		FGFR3_HUMAN (485-851): 5.88e-101: 333: 31.28
+	Hs
		901476 S61A1_HUMAN (1-476): 0: 717: 100.00		NTRK3_HUMAN (551-849): 3.61e-99: 329: 42.63
+	Hs
		435593 S61A1_HUMAN (1-476): 0: 717: 100.00		IGF1R_HUMAN (535-845): 9.34e-58: 217: 40.13
+	Hs
		411348 S61A1_HUMAN (1-476): 0: 717: 100.00		INSR_HUMAN (511-849): 1.55e-55: 210: 37.76
+	Hs
		901459 S61A1_HUMAN (1-476): 0: 717: 100.00		ROR2_HUMAN (551-854): 8.47e-56: 209: 38.39
+	Rn
		544803 S61A1_RAT (1-476): 0: 717: 100.00		INSR_RAT (511-849): 4.34e-54: 206: 37.46