HitPredict

Interactor 1: H3 (P61830)
Histone H3
Gene: HHT1

Interactor 2: HOS3 (Q02959)
Histone deacetylase HOS3 (EC 3.5.1.98)
Gene: HOS3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	19379692, 37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Sc			1 697
+	Hs
		935063 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		HDAC2_HUMAN (48-600): 1.44e-139: 419: 10.81
+	Hs
		952512 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		HDAC2_HUMAN (48-600): 1.44e-139: 419: 10.81
+	Hs
		1086250 H31T_HUMAN (1-136): 1.96e-61: 186: 86.03		HDAC2_HUMAN (48-600): 1.44e-139: 419: 10.81
+	Hs
		934735 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		HDAC1_HUMAN (47-552): 3.39e-136: 410: 11.94
+	Hs
		952319 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		HDAC1_HUMAN (47-552): 3.39e-136: 410: 11.94
+	Hs
		1038423 H31T_HUMAN (1-136): 1.96e-61: 186: 86.03		HDAC1_HUMAN (47-552): 3.39e-136: 410: 11.94
+	Hs
		111560 K7EK07_HUMAN (1-132): 8.05e-60: 182: 90.91		HDAC1_HUMAN (47-552): 3.39e-136: 410: 11.94
+	Hs
		177255 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		HDAC3_HUMAN (50-547): 3.34e-126: 383: 12.23
+	Hs
		935381 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		HDAC5_HUMAN (3-468): 3.38e-118: 382: 16.67
+	Hs
		952704 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		HDAC5_HUMAN (3-468): 3.38e-118: 382: 16.67
+	Hs
		1086354 H31T_HUMAN (1-136): 1.96e-61: 186: 86.03		HDAC5_HUMAN (3-468): 3.38e-118: 382: 16.67
+	Mm
		952741 H33_MOUSE (1-136): 1.25e-61: 187: 90.44		Q3UJF1_MOUSE (3-520): 7.44e-117: 378: 15.67
+	Mm
		952773 H33_MOUSE (1-136): 1.25e-61: 187: 90.44		Q9JM08_MOUSE (50-547): 4.38e-124: 377: 12.23
+	Sc
		693050 H3_YEAST (1-136): 1.51e-56: 174: 100.00		RPD3_YEAST (39-532): 9.42e-126: 382: 11.85
+	Hs
		952692 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		HDAC9_HUMAN (29-446): 1.27e-108: 354: 17.82
+	Hs
		1174685 H32_HUMAN (1-136): 6.6e-61: 185: 88.97		HDAC9_HUMAN (29-446): 1.27e-108: 354: 17.82
+	Hs
		935331 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		HDAC6_HUMAN (68-433): 3.94e-75: 265: 19.78
+	Sc
		866875 H3_YEAST (1-136): 1.51e-56: 174: 100.00		HDA1_YEAST (49-438): 3.75e-60: 216: 19.70
+	Sp
		140575 H31_SCHPO (1-136): 1.17e-59: 182: 92.65		PHD1_SCHPO (64-428): 7.52e-19: 91.9: 13.93
+	Sc
		859059 H3_YEAST (1-136): 1.51e-56: 174: 100.00		HOS2_YEAST (47-390): 1.81e-18: 90.7: 14.99