HitPredict

Interactor 1: H3 (P61830)
Histone H3
Gene: HHT1

Interactor 2: RUVB1 (Q03940)
RuvB-like protein 1 (RUVBL1) (EC 3.6.4.12) (TIP49-homology protein 1) (TIP49a homolog)
Gene: RVB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.641

Property	Details
Experiments	22199229, 24034245, 21179020
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 136 Sc			1 463
+	Hs
		935386 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		RUVB2_HUMAN (1-458): 0: 637: 41.09
+	Hs
		1174695 H32_HUMAN (1-136): 6.6e-61: 185: 88.97		RUVB2_HUMAN (1-458): 0: 637: 41.09
+	Sc
		730910 CENPA_YEAST (24-134): 7.32e-41: 137: 53.04		RUVB1_YEAST (1-463): 0: 682: 100.00
+	Hs
		828426 CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73		RUVB1_HUMAN (2-461): 0: 682: 67.61
+	Sc
		902155 H3_YEAST (1-136): 1.51e-56: 174: 100.00		RUVB2_YEAST (15-463): 0: 622: 41.15
+	Hs
		828425 CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73		RUVB2_HUMAN (1-458): 0: 637: 41.09
+	Sc
		730956 CENPA_YEAST (24-134): 7.32e-41: 137: 53.04		RUVB2_YEAST (15-463): 0: 622: 41.15