HitPredict

Interactor 1: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Interactor 2: PCGF1 (Q9BSM1)
Polycomb group RING finger protein 1 (Nervous system Polycomb-1) (NSPc1) (RING finger protein 68)
Gene: PCGF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 342 Hs			1 259
+	Hs
		718385 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		PCGF2_HUMAN (30-255): 4.65e-59: 192: 35.57
+	Hs
		902923 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		PCGF3_HUMAN (32-257): 1.89e-56: 182: 38.68
+	Hs
		903017 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		PCGF6_HUMAN (26-252): 6.21e-45: 156: 36.05
+	Hs
		902951 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		PCGF5_HUMAN (30-257): 3.38e-44: 151: 29.41
+	Hs
		903005 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Mm
		903076 DCAF7_MOUSE (1-342): 5.45e-87: 267: 100.00		RING2_MOUSE (24-259): 5.08e-39: 140: 16.88
+	Mm
		1194979 Q80ZU1_MOUSE (1-342): 2.67e-85: 262: 99.71		RING2_MOUSE (24-259): 5.08e-39: 140: 16.88
+	Hs
		718223 SC31B_HUMAN (23-336): 4.36e-52: 187: 17.38		BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29
+	Hs
		902886 DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00		RING1_HUMAN (24-155): 3.14e-32: 123: 20.59
+	Mm
		1141971 RBBP7_MOUSE (10-342): 1.03e-68: 222: 14.51		RING2_MOUSE (24-259): 5.08e-39: 140: 16.88
+	Mm
		1141950 RBBP4_MOUSE (10-342): 2.39e-68: 221: 13.98		RING2_MOUSE (24-259): 5.08e-39: 140: 16.88
+	Hs
		997870 RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Hs
		1083377 RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51		TRI31_HUMAN (32-246): 2.35e-32: 124: 17.27
+	Dm
		1279331 EBI_DROME (104-342): 5.77e-41: 153: 15.98		Q9VV77_DROME (32-257): 1.29e-53: 174: 39.30
+	Hs
		717626 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29
+	Hs
		282637 RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98		RNF8_HUMAN (24-130): 3e-10: 61.7: 28.04
+	Hs
		903455 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Mm
		903677 WDR5_MOUSE (208-342): 8.98e-29: 115: 11.85		RING2_MOUSE (24-259): 5.08e-39: 140: 16.88
+	Hs
		903159 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		RING1_HUMAN (24-155): 3.14e-32: 123: 20.59
+	Hs
		282600 WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85		RNF8_HUMAN (24-130): 3e-10: 61.7: 28.04