HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33022573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 471
+	Hs
		903196 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42
+	Hs
		903390 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41
+	Hs
		516438 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		613398 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92
+	Hs
		1069762 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		NONO_HUMAN (1-471): 1.15e-97: 303: 100.00
+	Hs
		1263497 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41
+	Hs
		613543 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92
+	Hs
		1077517 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Hs
		1308786 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		RBM4B_HUMAN (75-182): 7.1e-09: 59.3: 35.71
+	Hs
		1314629 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		RBM4_HUMAN (75-182): 7.64e-09: 59.3: 35.71
+	Hs
		1222300 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		RAVR1_HUMAN (76-221): 8.34e-12: 69.4: 24.70