HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: PELP1 (Q8IZL8)
Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of non-genomic activity of estrogen receptor) (Transcription factor HMX3)
Gene: PELP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	15960975
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0071339 - MLL1 complex
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 1130
+	Hs
		1224517 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		PELP1_HUMAN (1-1130): 0: 788: 100.00
+	Hs
		903405 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		CBP_HUMAN (631-1010): 2.14e-28: 126: 16.87
+	Mm
		903669 WDR5_MOUSE (1-334): 2.77e-131: 379: 100.00		KMT2C_MOUSE (657-1128): 5.97e-12: 72.8: 9.28
+	Hs
		903172 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		EP300_HUMAN (697-1081): 1.18e-11: 71.5: 11.17
+	Hs
		903374 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		KMT2C_HUMAN (704-1130): 8.21e-11: 68.9: 9.28
+	Hs
		209436 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		MDC1_HUMAN (411-1014): 5.18e-12: 72.8: 11.24
+	Hs
		209428 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		EP300_HUMAN (697-1081): 1.18e-11: 71.5: 11.17
+	Hs
		998787 SMU1_HUMAN (30-331): 7.66e-39: 145: 28.71		EP300_HUMAN (697-1081): 1.18e-11: 71.5: 11.17
+	Hs
		1302927 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		MINT_HUMAN (731-1119): 1.09e-10: 68.5: 12.18
+	Hs
		1056932 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		MDC1_HUMAN (411-1014): 5.18e-12: 72.8: 11.24
+	Hs
		1288258 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		MINT_HUMAN (731-1119): 1.09e-10: 68.5: 12.18