HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33022573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 523
+	Hs
		516438 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		903241 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		613398 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		903196 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		PABP4_HUMAN (3-149): 2.52e-27: 118: 18.83
+	Hs
		1263497 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		1069762 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		613543 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		1077517 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		1308786 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		RBM4B_HUMAN (83-190): 4.07e-09: 60.5: 33.04
+	Hs
		1314629 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		RBM4_HUMAN (83-190): 4.98e-09: 60.1: 32.14
+	Hs
		1222300 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		RAVR1_HUMAN (84-234): 5.69e-14: 76.4: 23.35