HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: WDR26 (Q9H7D7)
WD repeat-containing protein 26 (CUL4- and DDB1-associated WDR protein 2) (Myocardial ischemic preconditioning up-regulated protein 2)
Gene: WDR26

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17041588
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 661
+	Hs
		792949 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		LIS1_HUMAN (394-661): 1.17e-77: 255: 15.23
+	Hs
		903418 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		FBXW7_HUMAN (314-594): 9.42e-60: 214: 14.53
+	Hs
		903349 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		WDR5B_HUMAN (179-512): 1.46e-45: 166: 14.29
+	Hs
		903077 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		792935 LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49		LIS1_HUMAN (394-661): 1.17e-77: 255: 15.23
+	Mm
		925836 LIS1_MOUSE (2-289): 1.02e-94: 288: 29.49		LIS1_MOUSE (394-661): 7.74e-78: 255: 15.23
+	Hs
		903551 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		NLE1_HUMAN (45-428): 8.11e-31: 128: 15.25
+	Hs
		282871 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		CIAO1_HUMAN (359-641): 1.55e-15: 80.5: 26.18
+	Hs
		903428 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		SNR40_HUMAN (17-381): 1.88e-13: 74.4: 13.39
+	Dm
		1358845 WDS_DROME (3-290): 7.53e-92: 279: 31.21		WDS_DROME (519-661): 5.87e-42: 157: 19.58
+	Hs
		209416 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		245633 TBL1R_HUMAN (82-333): 6.52e-60: 201: 26.28		TBL1X_HUMAN (396-661): 8.44e-63: 220: 19.79
+	Hs
		1309163 TBL1R_HUMAN (82-333): 6.52e-60: 201: 26.28		TBL1Y_HUMAN (396-661): 1.24e-60: 213: 19.72
+	Hs
		282843 LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49		CIAO1_HUMAN (359-641): 1.55e-15: 80.5: 26.18
+	Hs
		1146788 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		A16L1_HUMAN (522-652): 1.81e-24: 110: 18.94
+	Hs
		209467 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		SNR40_HUMAN (17-381): 1.88e-13: 74.4: 13.39
+	Hs
		1240442 POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89		POC1A_HUMAN (61-383): 1.79e-14: 77.9: 12.00
+	Mm
		1207776 WDR83_MOUSE (26-333): 3.34e-84: 258: 32.69		A16L1_MOUSE (356-473): 6.39e-15: 80.1: 19.67
+	Hs
		1288273 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		SNR40_HUMAN (17-381): 1.88e-13: 74.4: 13.39