HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: HCFC2 (Q9Y5Z7)
Host cell factor 2 (HCF-2) (C2 factor)
Gene: HCFC2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.735

The method score is based on:

Property Details
Experiments 15199122, 24981860, 26186194, 28514442, 27705803, 33961781
Identification Methods biochemical, affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006355 - regulation of DNA-templated transcription
GO:0006357 - regulation of transcription by RNA polymerase II
and 4 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 334
Hs

1 792
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024