Protein: KIME
Mevalonate kinase (MK) (EC 2.7.1.36)

Gene: KIME, MVK
Organism: Homo sapiens
Interactions: 40
UniProt ID: Q03426

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004496 - mevalonate kinase activity
GO:0005524 - ATP binding
GO:0005777 - peroxisome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1042696

KIME
Mevalonate kinase

7

3

Small-scale

0.967

High

1042705

CCD91
Coiled-coil domain-containing protein 91

3

0

High-throughput

0.638

High

1042720

TACC3
Transforming acidic coiled-coil-containing protein 3

2

0

High-throughput

0.602

High

842198

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

0

High-throughput

0.513

High

1042707

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.513

High

1042712

TRNT1
CCA tRNA nucleotidyltransferase 1, mitochondrial

1

0

High-throughput

0.513

High

1042713

NJMU
Protein Njmu-R1

1

0

High-throughput

0.513

High

1042714

ANLN
Anillin

1

0

High-throughput

0.513

High

537011

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

1042716

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

295572

CIB2
Calcium and integrin-binding family member 2

1

0

High-throughput

0.426

High

1042718

GAB2
GRB2-associated-binding protein 2

1

0

High-throughput

0.426

High

886778

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

1042708

SACA4
Sperm acrosome membrane-associated protein 4

3

0

High-throughput

0.347

High

1042702

KLH10
Kelch-like protein 10

3

0

High-throughput

0.345

High

782987

GGT5
Glutathione hydrolase 5 proenzyme

2

0

High-throughput

0.328

High

1042701

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

2

0

High-throughput

0.328

High

1032911

EWS
RNA-binding protein EWS

2

0

High-throughput

0.317

High

1042709

RN141
RING finger protein 141

2

0

High-throughput

0.316

High

1042715

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.299

High

928425

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.288

High

50095

S22AN
Solute carrier family 22 member 23

1

0

High-throughput

0.279

Low

554216

BMP4
Bone morphogenetic protein 4

1

0

High-throughput

0.279

Low

574014

HXB2
Homeobox protein Hox-B2

1

0

High-throughput

0.279

Low

1042699

NAB1
NGFI-A-binding protein 1

1

0

High-throughput

0.279

Low

1042700

DOC2A
Double C2-like domain-containing protein alpha

1

0

High-throughput

0.279

Low

1042706

LYRIC
Protein LYRIC

1

0

High-throughput

0.279

Low

1042710

ANR49
Ankyrin repeat domain-containing protein 49

1

0

High-throughput

0.279

Low

1042711

ESIP1
Epithelial-stromal interaction protein 1

1

0

High-throughput

0.279

Low

1042717

LEF1
Lymphoid enhancer-binding factor 1

1

0

High-throughput

0.279

Low

1042719

BACE2
Beta-secretase 2

1

0

High-throughput

0.279

Low

258278

TRI13
E3 ubiquitin-protein ligase TRIM13

1

0

High-throughput

0.269

Low

1042704

PCAT2
Lysophosphatidylcholine acyltransferase 2

1

0

High-throughput

0.269

Low

588513

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

695262

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

768004

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1042703

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1042697

NOTC2
Neurogenic locus notch homolog protein 2

1

0

High-throughput

0.232

Low

1042698

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025