HitPredict

Interactor 1: HNRPK (P61979)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K)
Gene: Hnrnpk

Interactor 2: SRSF3 (P84104)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Protein X16) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	26336360, 34133714
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0008380 - RNA splicing GO:0048024 - regulation of mRNA splicing, via spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 463 Mm			1 164
+	Mm
		904289 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		SRSF7_MOUSE (7-115): 1.47e-26: 102: 60.55
+	Hs
		903884 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00
+	Mm
		904278 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		SRSF1_MOUSE (9-80): 1.1e-25: 100: 48.65
+	Mm
		192620 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		SRSF5_MOUSE (10-112): 1.98e-24: 97: 44.34
+	Mm
		904361 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		SRS10_MOUSE (1-164): 2.25e-24: 96.6: 32.54
+	Hs
		853838 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14
+	Hs
		516439 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Mm
		665747 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		PABP1_MOUSE (1-91): 1.3e-20: 89.2: 25.77
+	Mm
		904294 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		RBM4_MOUSE (11-88): 2.36e-18: 82.2: 28.21
+	Hs
		904110 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		RBM4_HUMAN (11-88): 3.45e-18: 81.9: 28.21
+	Dm
		2536 NOVA_DROME (40-224): 1.12e-32: 133: 25.13		Q9VYD8_DROME (7-80): 2.07e-25: 97: 70.27
+	Dm
		2420 NOVA_DROME (40-224): 1.12e-32: 133: 25.13		RX21_DROME (10-81): 7.87e-22: 88.6: 54.17
+	Hs
		884293 PCBP3_HUMAN (2-114): 1.36e-12: 70.9: 16.24		SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00
+	Hs
		951975 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00
+	Hs
		266997 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54
+	Hs
		853901 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14
+	Hs
		853956 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14
+	Hs
		516531 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Hs
		963557 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		TIAR_HUMAN (1-95): 5.6e-18: 81.1: 26.00
+	Hs
		993723 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		SRSF4_HUMAN (11-112): 3.43e-16: 76.6: 39.22