HitPredict

Interactor 1: HNRPK (P61979)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K)
Gene: Hnrnpk

Interactor 2: PTBP3 (Q8BHD7)
Polypyrimidine tract-binding protein 3 (Regulator of differentiation 1) (Rod1)
Gene: PTBP3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26336360
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0006397 - mRNA processing GO:0008380 - RNA splicing GO:0048025 - negative regulation of mRNA splicing, via spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 463 Mm			1 523
+	Hs
		643466 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		PTBP1_HUMAN (4-523): 5.06e-101: 316: 74.72
+	Hs
		904052 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		HNRLL_HUMAN (15-522): 3.17e-62: 214: 23.65
+	Hs
		540949 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		HNRPL_HUMAN (18-520): 1.43e-59: 208: 23.57
+	Mm
		904303 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		HNRPL_MOUSE (18-520): 1.85e-59: 208: 23.38
+	Mm
		1265263 NOVA1_MOUSE (1-460): 9.32e-78: 253: 19.51		PTBP2_MOUSE (2-523): 3.45e-86: 277: 66.16
+	Rn
		904410 HNRPK_RAT (1-463): 1.31e-129: 385: 100.00		Q9ET33_RAT (397-521): 1.18e-37: 137: 27.21
+	Hs
		516439 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		PABP1_HUMAN (232-523): 2.74e-31: 129: 12.38
+	Mm
		665747 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		PABP1_MOUSE (232-523): 3.33e-31: 129: 12.38
+	Hs
		643461 PCBP3_HUMAN (2-114): 1.36e-12: 70.9: 16.24		PTBP1_HUMAN (4-523): 5.06e-101: 316: 74.72
+	Hs
		643515 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		PTBP1_HUMAN (4-523): 5.06e-101: 316: 74.72
+	Hs
		321265 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		PTBP3_HUMAN (1-523): 1.12e-100: 315: 94.65
+	Dm
		2394 NOVA_DROME (40-224): 1.12e-32: 133: 25.13		A1ZBN3_DROME (253-521): 5.57e-67: 223: 25.61
+	Hs
		1072203 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		PTBP2_HUMAN (11-523): 2.44e-85: 275: 67.32
+	Hs
		1273092 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		PTBP2_HUMAN (11-523): 2.44e-85: 275: 67.32
+	Hs
		884365 PCBP3_HUMAN (2-114): 1.36e-12: 70.9: 16.24		PTBP2_HUMAN (11-523): 2.44e-85: 275: 67.32
+	Ce
		1325686 Q9GRY9_CAEEL (8-224): 1.53e-27: 115: 19.91		Q9XVS2_CAEEL (30-401): 3.44e-56: 196: 16.39
+	Hs
		884335 PCBP3_HUMAN (2-114): 1.36e-12: 70.9: 16.24		HNRLL_HUMAN (15-522): 3.17e-62: 214: 23.65
+	Hs
		541017 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		HNRPL_HUMAN (18-520): 1.43e-59: 208: 23.57
+	Mm
		888825 PCBP1_MOUSE (23-127): 3.42e-12: 69.7: 23.15		HNRPL_MOUSE (18-520): 1.85e-59: 208: 23.38
+	Hs
		516531 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		PABP1_HUMAN (232-523): 2.74e-31: 129: 12.38