HitPredict

Interactor 1: GATA4 (P43694)
Transcription factor GATA-4 (GATA-binding factor 4)
Gene: GATA4

Interactor 2: ID2 (Q02363)
DNA-binding protein inhibitor ID-2 (Class B basic helix-loop-helix protein 26) (bHLHb26) (Inhibitor of DNA binding 2) (Inhibitor of differentiation 2)
Gene: ID2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	16556596
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 442 Hs			1 134
+	Hs
		780951 GATA4_HUMAN (1-442): 5.21e-80: 256: 100.00		ID1_HUMAN (14-133): 1.58e-45: 146: 45.39
+	Hs
		798865 GATA4_HUMAN (1-442): 5.21e-80: 256: 100.00		ID3_HUMAN (1-133): 8.38e-44: 141: 39.13