HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: M3K21 (Q5TCX8)
Mitogen-activated protein kinase kinase kinase 21 (EC 2.7.11.25) (Mitogen-activated protein kinase kinase kinase MLK4) (Mixed lineage kinase 4)
Gene: MAP3K21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.932

The method score is based on:

Property Details
Experiments 32707033, 33961781, 35271311, 36931259, 28514442
Identification Methods affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains 14-3-3~PK_Tyr_Ser-Thr
Common GO terms GO:0005737 - cytoplasm
GO:0007165 - signal transduction
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 247
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024