Protein: SNX9
Sorting nexin-9 (SH3 and PX domain-containing protein 1) (Protein SDP1) (SH3 and PX domain-containing protein 3A)

Gene: SNX9
Organism: Homo sapiens
Interactions: 177
UniProt ID: Q9Y5X1

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0001726 - ruffle
GO:0005545 - 1-phosphatidylinositol binding
GO:0005737 - cytoplasm
GO:0005802 - trans-Golgi network

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

896948

DYN2
Dynamin-2

8

15

Small-scale

0.979

High

1050728

DYN1
Dynamin-1

7

15

Small-scale

0.968

High

1462656

DYN3
Dynamin-3

4

15

High-throughput

0.900

High

1060817

ACK1
Activated CDC42 kinase 1

3

16

Small-scale

0.866

High

1491759

SNX9
Sorting nexin-9

3

17

Small-scale

0.861

High

1292593

FCSD1
F-BAR and double SH3 domains protein 1

3

9

High-throughput

0.855

High

1357705

SNX33
Sorting nexin-33

3

18

Small-scale

0.827

High

1251284

DNMBP
Dynamin-binding protein

3

5

High-throughput

0.805

High

463866

LYN
Tyrosine-protein kinase Lyn

2

8

High-throughput

0.754

High

215961

SYNJ1
Synaptojanin-1

4

5

Small-scale

0.702

High

869530

TNFL6
Tumor necrosis factor ligand superfamily member 6

4

2

Small-scale

0.694

High

170454

AURKA
Aurora kinase A

4

7

High-throughput

0.694

High

1105838

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

3

20

Small-scale

0.687

High

1105794

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

3

20

Small-scale

0.669

High

1060707

SOS1
Son of sevenless homolog 1

1

3

Small-scale

0.665

High

1060729

SOS2
Son of sevenless homolog 2

1

3

Small-scale

0.665

High

323808

AP2A2
AP-2 complex subunit alpha-2

3

6

High-throughput

0.662

High

344838

AP2A1
AP-2 complex subunit alpha-1

3

6

High-throughput

0.662

High

1386760

AP2M1
AP-2 complex subunit mu

3

2

High-throughput

0.662

High

1034091

OCRL
Inositol polyphosphate 5-phosphatase OCRL

3

6

High-throughput

0.656

High

364095

EGFR
Epidermal growth factor receptor

3

20

High-throughput

0.653

High

842674

WASP
Actin nucleation-promoting factor WAS

2

20

Small-scale

0.631

High

965958

HNRPK
Heterogeneous nuclear ribonucleoprotein K

2

1

High-throughput

0.628

High

1083340

AP1B1
AP-1 complex subunit beta-1

2

6

High-throughput

0.628

High

133700

WASL
Actin nucleation-promoting factor WASL

2

17

Small-scale

0.619

High

159935

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

2

High-throughput

0.618

High

463274

YES
Tyrosine-protein kinase Yes

1

8

High-throughput

0.618

High

557551

SRC
Proto-oncogene tyrosine-protein kinase Src

1

8

High-throughput

0.618

High

699907

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

3

Small-scale

0.618

High

840906

TEC
Tyrosine-protein kinase Tec

1

7

High-throughput

0.618

High

1401307

SNX18
Sorting nexin-18

1

17

Small-scale

0.618

High

1434355

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.618

High

1491760

SNX8
Sorting nexin-8

1

17

Small-scale

0.618

High

1461576

ASAP1
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

1

0

Small-scale

0.614

High

989179

AP2B1
AP-2 complex subunit beta

2

6

High-throughput

0.611

High

1271237

DPPA4
Developmental pluripotency-associated protein 4

3

2

High-throughput

0.609

High

1394645

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

3

Small-scale

0.604

High

1182878

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

2

3

High-throughput

0.602

High

1439083

CPNE5
Copine-5

2

0

High-throughput

0.602

High

922626

AP2S1
AP-2 complex subunit sigma

2

3

High-throughput

0.601

High

1453648

PALS2
Protein PALS2

1

0

High-throughput

0.589

High

184345

NPHP1
Nephrocystin-1

1

0

High-throughput

0.586

High

243425

PRKN
E3 ubiquitin-protein ligase parkin

2

9

High-throughput

0.584

High

348270

DCMC
Malonyl-CoA decarboxylase, mitochondrial

2

0

High-throughput

0.576

High

2961

A0A0D9SFE4
Dynamin-1

1

15

High-throughput

0.575

High

319251

FCSD2
F-BAR and double SH3 domains protein 2

1

8

High-throughput

0.575

High

1145459

RNPS1
RNA-binding protein with serine-rich domain 1

2

2

High-throughput

0.571

High

1322691

RPTOR
Regulatory-associated protein of mTOR

2

2

High-throughput

0.571

High

920542

DAPK1
Death-associated protein kinase 1

1

3

High-throughput

0.536

High

260739

RAMP1
Receptor activity-modifying protein 1

1

1

High-throughput

0.536

High

335529

SLU7
Pre-mRNA-splicing factor SLU7

1

1

High-throughput

0.536

High

564618

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.536

High

998141

CSK21
Casein kinase II subunit alpha

1

3

High-throughput

0.536

High

1030719

ANK2
Ankyrin-2

1

5

High-throughput

0.536

High

1110223

HDAC1
Histone deacetylase 1

1

2

High-throughput

0.536

High

1114776

CUL3
Cullin-3

1

3

High-throughput

0.536

High

1370505

CSN5
COP9 signalosome complex subunit 5

1

2

High-throughput

0.536

High

1393429

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

High-throughput

0.536

High

190528

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.513

High

721751

GCH1
GTP cyclohydrolase 1

1

0

High-throughput

0.513

High

834385

GARS
Glycine--tRNA ligase

1

0

High-throughput

0.513

High

844905

EAA1
Excitatory amino acid transporter 1

1

0

High-throughput

0.513

High

1154485

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.513

High

1387386

APC16
Anaphase-promoting complex subunit 16

1

0

High-throughput

0.513

High

1437532

CLXN
Calaxin

1

0

High-throughput

0.513

High

1452282

SL2A8
Solute carrier family 2, facilitated glucose transporter member 8

1

0

High-throughput

0.513

High

1452902

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.513

High

209916

ADA12
Disintegrin and metalloproteinase domain-containing protein 12

1

20

Small-scale

0.501

High

225868

AP1G1
AP-1 complex subunit gamma-1

1

5

Small-scale

0.501

High

839120

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

1

Small-scale

0.501

High

1005387

ADAM8
Disintegrin and metalloproteinase domain-containing protein 8

1

20

Small-scale

0.501

High

1209853

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.501

High

1429276

ADA19
Disintegrin and metalloproteinase domain-containing protein 19

1

20

Small-scale

0.501

High

508912

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

Small-scale

0.500

High

1248324

ARAID
All-trans retinoic acid-induced differentiation factor

1

0

Small-scale

0.493

High

937671

FOXG1
Forkhead box protein G1

1

2

High-throughput

0.489

High

1029796

FOXK2
Forkhead box protein K2

1

2

High-throughput

0.489

High

1185959

PCGF3
Polycomb group RING finger protein 3

1

5

High-throughput

0.489

High

1286277

PCGF5
Polycomb group RING finger protein 5

1

5

High-throughput

0.489

High

1295137

F90A1
Protein FAM90A1

1

3

High-throughput

0.489

High

1389129

KBP
KIF-binding protein

1

1

High-throughput

0.489

High

1398317

RN145
RING finger protein 145

1

3

High-throughput

0.489

High

1040959

MECOM
Histone-lysine N-methyltransferase MECOM

1

2

High-throughput

0.481

High

1361815

PI3R5
Phosphoinositide 3-kinase regulatory subunit 5

1

0

Small-scale

0.480

High

161110

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

20

Small-scale

0.479

High

212700

DAPK3
Death-associated protein kinase 3

1

1

High-throughput

0.479

High

270860

ROCK2
Rho-associated protein kinase 2

1

2

High-throughput

0.479

High

272581

OBSL1
Obscurin-like protein 1

1

2

High-throughput

0.479

High

346571

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

376149

RASK
GTPase KRas

1

15

High-throughput

0.479

High

412894

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.479

High

459823

PROF1
Profilin-1

1

1

High-throughput

0.479

High

556445

CADH1
Cadherin-1

1

3

High-throughput

0.479

High

590147

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

766986

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

799615

BRCA1
Breast cancer type 1 susceptibility protein

1

4

High-throughput

0.479

High

831728

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

845877

MUC18
Cell surface glycoprotein MUC18

1

2

High-throughput

0.479

High

888421

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.479

High

955796

CDC42
Cell division control protein 42 homolog

1

4

High-throughput

0.479

High

995372

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.479

High

1004250

CXAR
Coxsackievirus and adenovirus receptor

1

1

High-throughput

0.479

High

1008464

ADA17
Disintegrin and metalloproteinase domain-containing protein 17

1

20

Small-scale

0.479

High

1026302

CLH1
Clathrin heavy chain 1

1

3

Small-scale

0.479

High

1067887

EP300
Histone acetyltransferase p300

1

6

High-throughput

0.479

High

1115175

CUL4A
Cullin-4A

1

3

High-throughput

0.479

High

1142047

EEA1
Early endosome antigen 1

1

2

High-throughput

0.479

High

1156633

CCDC6
Coiled-coil domain-containing protein 6

1

2

High-throughput

0.479

High

1159922

OCLN
Occludin

1

2

High-throughput

0.479

High

1235701

NIPBL
Nipped-B-like protein

1

1

High-throughput

0.479

High

1249371

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

1256286

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.479

High

1289753

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1308768

M4K3
Mitogen-activated protein kinase kinase kinase kinase 3

1

6

High-throughput

0.479

High

1329969

SIR6
NAD-dependent protein deacylase sirtuin-6

1

2

High-throughput

0.479

High

1350518

BICD2
Protein bicaudal D homolog 2

1

5

High-throughput

0.479

High

1353164

FBF1
Fas-binding factor 1

1

6

High-throughput

0.479

High

1360855

ASB11
Ankyrin repeat and SOCS box protein 11

1

3

High-throughput

0.479

High

1364743

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

4

High-throughput

0.479

High

1382021

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.479

High

1391222

BICD1
Protein bicaudal D homolog 1

1

5

High-throughput

0.479

High

1398425

CEP63
Centrosomal protein of 63 kDa

1

3

High-throughput

0.479

High

1400357

FMNL2
Formin-like protein 2

1

5

High-throughput

0.479

High

1420394

TRI31
E3 ubiquitin-protein ligase TRIM31

1

10

High-throughput

0.479

High

1429039

WWTR1
WW domain-containing transcription regulator protein 1

1

9

High-throughput

0.479

High

1435513

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

1448269

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

2

High-throughput

0.479

High

1453072

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

1454803

ANFY1
Rabankyrin-5

1

5

High-throughput

0.479

High

1460340

XPO7
Exportin-7

1

8

High-throughput

0.479

High

1491439

M4K5
Mitogen-activated protein kinase kinase kinase kinase 5

1

6

High-throughput

0.479

High

294596

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

316228

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

643168

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.458

High

657723

GCSP
Glycine dehydrogenase

1

0

High-throughput

0.458

High

958231

ARP3
Actin-related protein 3

1

0

High-throughput

0.458

High

971368

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1029981

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.458

High

1233251

NADE
Glutamine-dependent NAD(+) synthetase

1

0

High-throughput

0.458

High

1459538

TES
Testin

1

0

High-throughput

0.458

High

1461289

AGO2
Protein argonaute-2

1

0

Small-scale

0.458

High

1491761

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

0

High-throughput

0.458

High

1195719

Q4LE69
Phosphatidylinositol 4-kinase alpha

1

1

Small-scale

0.457

High

176282

SYNJ2
Synaptojanin-2

1

5

High-throughput

0.445

High

284635

ECI2
Enoyl-CoA delta isomerase 2

1

2

High-throughput

0.445

High

411141

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.445

High

766064

BMI1
Polycomb complex protein BMI-1

1

5

High-throughput

0.445

High

889358

NUMB
Protein numb homolog

1

2

High-throughput

0.445

High

964784

DCAF7
DDB1- and CUL4-associated factor 7

1

3

High-throughput

0.445

High

1070524

FCHO2
F-BAR domain only protein 2

1

3

High-throughput

0.445

High

1092692

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

2

High-throughput

0.445

High

1227792

A16L1
Autophagy-related protein 16-1

1

4

High-throughput

0.445

High

1353776

WIPF2
WAS/WASL-interacting protein family member 2

1

2

High-throughput

0.445

High

1447633

BIN3
Bridging integrator 3

1

7

High-throughput

0.445

High

1491762

NUMBL
Numb-like protein

1

3

High-throughput

0.445

High

1405183

MPH6
M-phase phosphoprotein 6

1

0

High-throughput

0.438

High

106930

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

260660

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.437

High

262583

MCE1
mRNA-capping enzyme

1

3

High-throughput

0.437

High

696987

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.437

High

769631

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

1096886

RFA4
Replication protein A 30 kDa subunit

1

5

High-throughput

0.437

High

1277047

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.437

High

1401477

CIC
Protein capicua homolog

1

3

High-throughput

0.437

High

1409916

ZFY21
Zinc finger FYVE domain-containing protein 21

1

9

Small-scale

0.437

High

1086197

CETN1
Centrin-1

1

0

High-throughput

0.426

High

1437437

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

1491764

MORC2
ATPase MORC2

1

0

High-throughput

0.426

High

887387

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.408

High

1060011

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

4

Small-scale

0.408

High

166723

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

0

High-throughput

0.279

Low

1431410

MED28
Mediator of RNA polymerase II transcription subunit 28

1

0

Small-scale

0.269

Low

1103479

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.249

Low

1286758

CLC14
C-type lectin domain family 14 member A

1

0

Small-scale

0.249

Low

1491763

SCC4
MAU2 chromatid cohesion factor homolog

1

0

High-throughput

0.249

Low

1437565

FBRS
Probable fibrosin-1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025