HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: SYDE2 (Q5VT97)
Rho GTPase-activating protein SYDE2 (Synapse defective protein 1 homolog 2) (Protein syd-1 homolog 2)
Gene: SYDE2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	33961781, 35271311, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 1194
+	Hs
		909659 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SYDE2_HUMAN (1-1194): 0: 1320: 100.00
+	Hs
		70666 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MYO9A_HUMAN (296-1193): 1.72e-102: 360: 15.15
+	Hs
		70665 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		MYO9A_HUMAN (296-1193): 1.72e-102: 360: 15.15
+	Hs
		909650 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		RHG21_HUMAN (373-1189): 9.41e-95: 336: 17.25
+	Hs
		909718 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SYDE1_HUMAN (428-1188): 1.17e-98: 332: 36.25
+	Hs
		904676 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		RHG21_HUMAN (373-1189): 9.41e-95: 336: 17.25
+	Hs
		904754 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SYDE1_HUMAN (428-1188): 1.17e-98: 332: 36.25
+	Hs
		909743 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SRGP1_HUMAN (397-1183): 4.61e-90: 316: 12.90
+	Mm
		910285 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		SRGP3_MOUSE (397-1174): 3.24e-89: 314: 11.72
+	Hs
		904781 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SRGP1_HUMAN (397-1183): 4.61e-90: 316: 12.90
+	Mm
		910322 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		SRGP2_MOUSE (397-1194): 6.45e-83: 295: 13.95
+	Hs
		253335 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		SRGP2_HUMAN (397-1194): 2.33e-81: 291: 13.95
+	Hs
		253334 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SRGP2_HUMAN (397-1194): 2.33e-81: 291: 13.95
+	Hs
		506563 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		BCR_HUMAN (533-1038): 3.93e-72: 265: 23.85
+	Hs
		910011 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		RGAP1_HUMAN (529-1118): 3.07e-75: 264: 16.67
+	Hs
		506562 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		BCR_HUMAN (533-1038): 3.93e-72: 265: 23.85
+	Hs
		904647 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		RHG29_HUMAN (813-1186): 3.93e-60: 228: 20.51
+	Hs
		909873 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		HMHA1_HUMAN (813-1050): 1.28e-55: 213: 28.00
+	Hs
		64684 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		RHG32_HUMAN (783-1026): 1.32e-54: 211: 27.53
+	Hs
		64683 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		RHG32_HUMAN (783-1026): 1.32e-54: 211: 27.53