HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: CARL2 (Q6F5E8)
Capping protein, Arp2/3 and myosin-I linker protein 2 (Capping protein regulator and myosin 1 linker 2) (F-actin-uncapping protein RLTPR) (Leucine-rich repeat-containing protein 16C) (RGD, leucine-rich repeat, tropomodulin and proline-rich-containing protein)
Gene: CARMIL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.60	0.554

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 247 Hs			1 1435
+	Hs
		909677 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		CARL2_HUMAN (1-1435): 0: 670: 100.00
+	Hs
		982138 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		CARL2_HUMAN (1-1435): 0: 670: 100.00
+	Hs
		683441 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		CARL2_HUMAN (1-1435): 0: 670: 100.00
+	Hs
		927165 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		CARL2_HUMAN (1-1435): 0: 670: 100.00
+	Hs
		646998 1433T_HUMAN (2-245): 5.53e-105: 305: 70.33		CARL2_HUMAN (1-1435): 0: 670: 100.00
+	Hs
		904697 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		CARL1_HUMAN (39-1434): 1.02e-158: 517: 29.59
+	Hs
		982123 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		CARL1_HUMAN (39-1434): 1.02e-158: 517: 29.59
+	Hs
		684107 1433S_HUMAN (2-245): 1.86e-98: 289: 65.16		CARL1_HUMAN (39-1434): 1.02e-158: 517: 29.59
+	At
		186958 14332_ARATH (4-244): 1.39e-141: 398: 61.32		BRI1_ARATH (75-806): 2.9e-70: 260: 12.38