HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: REEP3 (Q6NUK4)
Receptor expression-enhancing protein 3
Gene: REEP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.50	0.636

Property	Details
Experiments	33961781, 35271311, 36931259, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 255
+	Hs
		909682 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		REEP3_HUMAN (1-255): 5.32e-107: 311: 100.00
+	Hs
		982144 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		REEP3_HUMAN (1-255): 5.32e-107: 311: 100.00
+	Hs
		910029 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		REEP4_HUMAN (1-250): 3.38e-91: 271: 53.70
+	Hs
		905114 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		REEP4_HUMAN (1-250): 3.38e-91: 271: 53.70
+	Hs
		909967 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		REEP2_HUMAN (1-250): 4.58e-86: 258: 50.39
+	Hs
		982500 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		REEP4_HUMAN (1-250): 3.38e-91: 271: 53.70
+	Hs
		905052 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		REEP2_HUMAN (1-250): 4.58e-86: 258: 50.39
+	Hs
		982435 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		REEP2_HUMAN (1-250): 4.58e-86: 258: 50.39
+	Hs
		683447 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		REEP3_HUMAN (1-255): 5.32e-107: 311: 100.00
+	Hs
		927170 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		REEP3_HUMAN (1-255): 5.32e-107: 311: 100.00
+	Hs
		910038 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		REEP1_HUMAN (1-162): 1.58e-72: 222: 73.46
+	Hs
		905124 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		REEP1_HUMAN (1-162): 1.58e-72: 222: 73.46
+	Hs
		982511 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		REEP1_HUMAN (1-162): 1.58e-72: 222: 73.46
+	Hs
		683713 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		REEP4_HUMAN (1-250): 3.38e-91: 271: 53.70
+	Hs
		683673 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		REEP2_HUMAN (1-250): 4.58e-86: 258: 50.39
+	Hs
		927467 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		REEP2_HUMAN (1-250): 4.58e-86: 258: 50.39
+	At
		788367 14331_ARATH (4-244): 4.02e-141: 397: 59.67		HA22K_ARATH (1-167): 1.06e-44: 150: 21.43
+	Hs
		683272 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		REEP5_HUMAN (1-125): 8.94e-59: 186: 28.57
+	Hs
		927402 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		REEP6_HUMAN (1-134): 2.18e-56: 181: 25.93
+	Zm
		42212 B6SRI4_MAIZE (2-245): 2.63e-140: 395: 60.16		A0A1D6NY22_MAIZE (13-61): 1.88e-17: 76.1: 30.61