Protein: RRP1
Ribosomal RNA processing protein 1 homolog A (Novel nuclear protein 1) (NNP-1) (Nucleolar protein Nop52) (RRP1-like protein)

Gene: RRP1
Organism: Homo sapiens
Interactions: 159
UniProt ID: P56182

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005694 - chromosome
GO:0005730 - nucleolus
GO:0006364 - rRNA processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

940173

MAK16
Protein MAK16 homolog

2

3

High-throughput

0.811

High

940116

RL18
Large ribosomal subunit protein eL18

2

2

High-throughput

0.789

High

940111

SRPK2
SRSF protein kinase 2

3

9

High-throughput

0.656

High

940125

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

2

High-throughput

0.646

High

940205

NGN3
Neurogenin-3

2

1

High-throughput

0.628

High

446809

NPM
Nucleophosmin

2

2

High-throughput

0.611

High

940131

IF16
Gamma-interferon-inducible protein 16

2

3

High-throughput

0.611

High

940176

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

2

1

High-throughput

0.611

High

262215

SCN2B
Sodium channel regulatory subunit beta-2

3

3

High-throughput

0.609

High

940148

VSIG1
V-set and immunoglobulin domain-containing protein 1

3

1

High-throughput

0.604

High

940153

PNKD
Probable thioesterase PNKD

2

0

High-throughput

0.585

High

345574

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

8

High-throughput

0.584

High

371584

MYC
Myc proto-oncogene protein

2

3

High-throughput

0.584

High

940106

RS6
Small ribosomal subunit protein eS6

2

2

High-throughput

0.584

High

940107

H4
Histone H4

2

2

High-throughput

0.584

High

940112

H33
Histone H3.3

2

4

High-throughput

0.584

High

940167

DDRGK
DDRGK domain-containing protein 1

2

1

Small-scale

0.584

High

640136

EPHA1
Ephrin type-A receptor 1

2

1

High-throughput

0.574

High

395770

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

940158

ESR2
Estrogen receptor beta

2

3

High-throughput

0.571

High

138661

IMA4
Importin subunit alpha-4

1

1

High-throughput

0.536

High

417347

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.536

High

479356

SRP19
Signal recognition particle 19 kDa protein

1

1

High-throughput

0.536

High

634378

LMNB1
Lamin-B1

1

1

High-throughput

0.536

High

833089

MNDA
Myeloid cell nuclear differentiation antigen

1

3

High-throughput

0.536

High

889698

CLK3
Dual specificity protein kinase CLK3

1

2

High-throughput

0.536

High

898564

RL14
Large ribosomal subunit protein eL14

1

1

High-throughput

0.536

High

940104

RS8
Small ribosomal subunit protein eS8

1

1

High-throughput

0.536

High

940109

RACK1
Small ribosomal subunit protein RACK1

1

5

High-throughput

0.536

High

940115

FAK1
Focal adhesion kinase 1

1

4

High-throughput

0.536

High

940129

OASL
2'-5'-oligoadenylate synthase-like protein

1

1

High-throughput

0.536

High

940157

DGCR8
Microprocessor complex subunit DGCR8

1

1

High-throughput

0.536

High

940171

RBM4B
RNA-binding protein 4B

1

4

High-throughput

0.536

High

940174

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

6

High-throughput

0.536

High

940202

SRPK3
SRSF protein kinase 3

1

7

High-throughput

0.536

High

940203

DRG1
Developmentally-regulated GTP-binding protein 1

1

3

High-throughput

0.536

High

940151

S15A3
Solute carrier family 15 member 3

2

1

High-throughput

0.521

High

158645

TYB4Y
Thymosin beta-4, Y-chromosomal

1

0

High-throughput

0.513

High

940113

EFNB1
Ephrin-B1

1

0

High-throughput

0.513

High

940160

EZH1
Histone-lysine N-methyltransferase EZH1

1

0

High-throughput

0.513

High

940186

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.513

High

940189

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.513

High

940200

TPX2
Targeting protein for Xklp2

1

0

High-throughput

0.513

High

940209

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.513

High

185566

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.501

High

60710

F234B
Protein FAM234B

1

1

High-throughput

0.489

High

940144

PNM8A
Paraneoplastic antigen-like protein 8A

1

2

High-throughput

0.489

High

940179

F234A
Protein FAM234A

1

1

High-throughput

0.489

High

940183

CLMP
CXADR-like membrane protein

1

1

High-throughput

0.489

High

940114

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.480

High

128901

MEN1
Menin

1

1

High-throughput

0.479

High

247773

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

315342

RECQ4
ATP-dependent DNA helicase Q4

1

8

High-throughput

0.479

High

385599

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.479

High

400553

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

405949

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.479

High

418903

H2A1B
Histone H2A type 1-B/E

1

1

High-throughput

0.479

High

536841

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

588326

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

620228

NUCL
Nucleolin

1

3

High-throughput

0.479

High

695053

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

809985

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.479

High

830430

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

854805

RECQ1
ATP-dependent DNA helicase Q1

1

4

High-throughput

0.479

High

872121

SOX2
Transcription factor SOX-2

1

4

High-throughput

0.479

High

904508

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.479

High

940105

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

940108

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.479

High

940110

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

940117

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

High-throughput

0.479

High

940118

GRSF1
G-rich sequence factor 1

1

8

High-throughput

0.479

High

940119

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

6

High-throughput

0.479

High

940120

NFX1
Transcriptional repressor NF-X1

1

1

High-throughput

0.479

High

940122

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

940126

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

6

High-throughput

0.479

High

940128

PCBP1
Poly(rC)-binding protein 1

1

5

High-throughput

0.479

High

940133

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

5

High-throughput

0.479

High

940134

MIDN
Midnolin

1

1

High-throughput

0.479

High

940135

HABP4
Intracellular hyaluronan-binding protein 4

1

1

High-throughput

0.479

High

940147

ZCH18
Zinc finger CCCH domain-containing protein 18

1

3

High-throughput

0.479

High

940155

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

940156

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

940159

KAT6A
Histone acetyltransferase KAT6A

1

5

High-throughput

0.479

High

940161

FBXW7
F-box/WD repeat-containing protein 7

1

2

High-throughput

0.479

High

940162

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

940169

RING2
E3 ubiquitin-protein ligase RING2

1

2

High-throughput

0.479

High

940170

BARD1
BRCA1-associated RING domain protein 1

1

1

High-throughput

0.479

High

940172

RIOK1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

940191

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

2

High-throughput

0.479

High

940193

AKIP
Small ribosomal subunit protein mS38

1

1

High-throughput

0.479

High

940194

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

2

High-throughput

0.479

High

940195

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

940197

XPO7
Exportin-7

1

3

High-throughput

0.479

High

940206

MAFB
Transcription factor MafB

1

3

High-throughput

0.479

High

940142

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

940149

RIOX2
Ribosomal oxygenase 2

1

0

High-throughput

0.458

High

940164

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

940188

NGRN
Neugrin

1

0

High-throughput

0.458

High

940192

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

429600

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

649275

H1T
Histone H1t

1

2

High-throughput

0.445

High

940132

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

1

High-throughput

0.445

High

940177

REXO4
RNA exonuclease 4

1

4

High-throughput

0.445

High

940204

YBOX2
Y-box-binding protein 2

1

2

High-throughput

0.445

High

272018

OBSL1
Obscurin-like protein 1

1

1

High-throughput

0.437

High

767817

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

878847

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.437

High

940127

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.437

High

940130

E2F4
Transcription factor E2F4

1

1

High-throughput

0.437

High

940137

A16L1
Autophagy-related protein 16-1

1

3

High-throughput

0.437

High

940140

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

940152

AHI1
Jouberin

1

7

Small-scale

0.437

High

940154

FBXL6
F-box/LRR-repeat protein 6

1

2

High-throughput

0.437

High

940166

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

1

High-throughput

0.437

High

940175

TRI31
E3 ubiquitin-protein ligase TRIM31

1

3

High-throughput

0.437

High

940182

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

940187

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

2

High-throughput

0.437

High

940190

ANLN
Anillin

1

1

High-throughput

0.437

High

940199

HECD1
E3 ubiquitin-protein ligase HECTD1

1

4

High-throughput

0.437

High

940207

DJC15
DnaJ homolog subfamily C member 15

1

1

High-throughput

0.437

High

601607

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.426

High

940141

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

High-throughput

0.426

High

104132

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

940103

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

1

High-throughput

0.407

High

940143

SO6A1
Solute carrier organic anion transporter family member 6A1

1

1

High-throughput

0.407

High

940145

LRRT4
Leucine-rich repeat transmembrane neuronal protein 4

1

1

High-throughput

0.407

High

940146

LRRT3
Leucine-rich repeat transmembrane neuronal protein 3

1

1

High-throughput

0.407

High

940181

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

1

High-throughput

0.407

High

940180

CHST8
Carbohydrate sulfotransferase 8

3

0

High-throughput

0.347

High

165796

TR13B
Tumor necrosis factor receptor superfamily member 13B

3

0

High-throughput

0.345

High

399559

VTNC
Vitronectin

2

0

High-throughput

0.328

High

940168

NECT4
Nectin-4

2

0

High-throughput

0.318

High

940136

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

2

0

High-throughput

0.316

High

940123

MOGS
Mannosyl-oligosaccharide glucosidase

2

0

High-throughput

0.313

High

71200

HIDE1
Protein HIDE1

1

0

High-throughput

0.279

Low

288167

CLC3A
C-type lectin domain family 3 member A

1

0

High-throughput

0.279

Low

388175

GLPA
Glycophorin-A

1

0

High-throughput

0.279

Low

418040

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.279

Low

505148

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

0

High-throughput

0.279

Low

749760

CADH5
Cadherin-5

1

0

High-throughput

0.279

Low

813046

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.279

Low

881647

FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

1

0

High-throughput

0.279

Low

940102

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.279

Low

940121

GAGE5
G antigen 5

1

0

High-throughput

0.279

Low

940139

BTNL9
Butyrophilin-like protein 9

1

0

High-throughput

0.279

Low

940150

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

940163

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

0

High-throughput

0.279

Low

940178

CHST5
Carbohydrate sulfotransferase 5

1

0

High-throughput

0.279

Low

940185

PACC1
Proton-activated chloride channel

1

0

High-throughput

0.279

Low

940198

ANR50
Ankyrin repeat domain-containing protein 50

1

0

High-throughput

0.279

Low

940208

NPTN
Neuroplastin

1

0

High-throughput

0.279

Low

219405

TNF12
Tumor necrosis factor ligand superfamily member 12

1

0

High-throughput

0.249

Low

940124

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.249

Low

940138

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

940165

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.249

Low

940184

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.249

Low

940196

TBK1
Serine/threonine-protein kinase TBK1

1

0

High-throughput

0.249

Low

940201

CAH14
Carbonic anhydrase 14

1

0

High-throughput

0.249

Low

171426

S27A2
Long-chain fatty acid transport protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025