Protein: KLK15
Kallikrein-15 (EC 3.4.21.-) (ACO protease)

Gene: KLK15
Organism: Homo sapiens
Interactions: 150
UniProt ID: Q9H2R5

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region
GO:0006508 - proteolysis
GO:0008236 - serine-type peptidase activity
GO:0030141 - secretory granule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

199478

SPIT1
Kunitz-type protease inhibitor 1

1

16

High-throughput

0.691

High

270327

LRP6
Low-density lipoprotein receptor-related protein 6

1

12

High-throughput

0.691

High

528132

BMP1
Bone morphogenetic protein 1

1

11

High-throughput

0.691

High

1085221

PRSS8
Prostasin

1

12

High-throughput

0.691

High

1329643

ST14
Suppressor of tumorigenicity 14 protein

1

17

High-throughput

0.691

High

933613

TBA4A
Tubulin alpha-4A chain

2

20

High-throughput

0.628

High

182288

TPSN
Tapasin

1

9

High-throughput

0.618

High

258345

LRP5
Low-density lipoprotein receptor-related protein 5

1

11

High-throughput

0.618

High

351104

LDLR
Low-density lipoprotein receptor

1

13

High-throughput

0.618

High

987549

APLP2
Amyloid beta precursor like protein 2

1

15

High-throughput

0.618

High

1241952

KREM2
Kremen protein 2

1

16

High-throughput

0.618

High

1329625

ANTR1
Anthrax toxin receptor 1

1

6

High-throughput

0.618

High

1329627

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

1

5

High-throughput

0.618

High

1329632

CELR1
Cadherin EGF LAG seven-pass G-type receptor 1

1

6

High-throughput

0.618

High

1329638

JAG2
Protein jagged-2

1

8

High-throughput

0.618

High

928687

DYLT1
Dynein light chain Tctex-type 1

2

1

High-throughput

0.606

High

213774

MCAT
Mitochondrial carnitine/acylcarnitine carrier protein

2

20

High-throughput

0.558

High

1310632

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

2

8

High-throughput

0.558

High

152910

APAF
Apoptotic protease-activating factor 1

1

3

High-throughput

0.536

High

302437

CSTN1
Calsyntenin-1

1

14

High-throughput

0.536

High

305314

NXPH4
Neurexophilin-4

1

1

High-throughput

0.536

High

434669

TSP1
Thrombospondin-1

1

14

High-throughput

0.536

High

437695

BGLR
Beta-glucuronidase

1

3

High-throughput

0.536

High

441637

TRFM
Melanotransferrin

1

3

High-throughput

0.536

High

536191

PERF
Perforin-1

1

1

High-throughput

0.536

High

580191

AMD
Peptidyl-glycine alpha-amidating monooxygenase

1

2

High-throughput

0.536

High

664192

PCSK6
Proprotein convertase subtilisin/kexin type 6

1

16

High-throughput

0.536

High

709276

GALNS
N-acetylgalactosamine-6-sulfatase

1

9

High-throughput

0.536

High

877450

LAMB2
Laminin subunit beta-2

1

8

High-throughput

0.536

High

1069166

PON2
Serum paraoxonase/arylesterase 2

1

5

High-throughput

0.536

High

1218323

GLBL2
Beta-galactosidase-1-like protein 2

1

2

High-throughput

0.536

High

1231531

VWDE
von Willebrand factor D and EGF domain-containing protein

1

12

High-throughput

0.536

High

1268718

GPI8
GPI-anchor transamidase

1

2

High-throughput

0.536

High

1290939

I17RA
Interleukin-17 receptor A

1

3

High-throughput

0.536

High

1310439

ADPGK
ADP-dependent glucokinase

1

2

High-throughput

0.536

High

1314820

CHID1
Chitinase domain-containing protein 1

1

3

High-throughput

0.536

High

1329626

RISC
Retinoid-inducible serine carboxypeptidase

1

2

High-throughput

0.536

High

1329637

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

1

14

High-throughput

0.536

High

1076531

TRIP6
Thyroid receptor-interacting protein 6

1

1

High-throughput

0.523

High

1116671

ERFE
Erythroferrone

1

0

High-throughput

0.513

High

59843

DEN11
DENN domain-containing protein 11

1

3

High-throughput

0.489

High

234994

SNX3
Sorting nexin-3

1

4

High-throughput

0.489

High

298790

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.489

High

299724

SUN1
SUN domain-containing protein 1

1

2

High-throughput

0.489

High

301234

RHBT3
Rho-related BTB domain-containing protein 3

1

5

High-throughput

0.489

High

313151

MOCS3
Adenylyltransferase and sulfurtransferase MOCS3

1

2

High-throughput

0.489

High

320572

OXSR1
Serine/threonine-protein kinase OSR1

1

6

High-throughput

0.489

High

330523

CLPT1
Putative lipid scramblase CLPTM1

1

1

High-throughput

0.489

High

335315

DYR
Dihydrofolate reductase

1

1

High-throughput

0.489

High

563901

NAGAB
Alpha-N-acetylgalactosaminidase

1

1

High-throughput

0.489

High

574576

ITB5
Integrin beta-5

1

7

High-throughput

0.489

High

708252

ERD22
ER lumen protein-retaining receptor 2

1

2

High-throughput

0.489

High

713421

BMP8B
Bone morphogenetic protein 8B

1

7

High-throughput

0.489

High

805473

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

4

High-throughput

0.489

High

829466

PPM1F
Protein phosphatase 1F

1

3

High-throughput

0.489

High

830106

MA2A2
Alpha-mannosidase 2x

1

7

High-throughput

0.489

High

872959

ANAG
Alpha-N-acetylglucosaminidase

1

2

High-throughput

0.489

High

942311

ASIC1
Acid-sensing ion channel 1

1

1

High-throughput

0.489

High

971063

DSC2
Desmocollin-2

1

5

High-throughput

0.489

High

981921

RON
Macrophage-stimulating protein receptor

1

20

High-throughput

0.489

High

993599

TLE5
TLE family member 5

1

2

High-throughput

0.489

High

1019238

HYAL2
Hyaluronidase-2

1

2

High-throughput

0.489

High

1034248

S39A6
Zinc transporter ZIP6

1

9

High-throughput

0.489

High

1034733

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

14

High-throughput

0.489

High

1040251

STIM1
Stromal interaction molecule 1

1

3

High-throughput

0.489

High

1052614

RCN2
Reticulocalbin-2

1

6

High-throughput

0.489

High

1053182

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

1

High-throughput

0.489

High

1069057

NOMO1
BOS complex subunit NOMO1

1

2

High-throughput

0.489

High

1088472

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

1

3

High-throughput

0.489

High

1114231

TBB8
Tubulin beta-8 chain

1

18

High-throughput

0.489

High

1115431

FUT11
Alpha-(1,3)-fucosyltransferase 11

1

2

High-throughput

0.489

High

1133334

GT253
Inactive glycosyltransferase 25 family member 3

1

7

High-throughput

0.489

High

1136954

BIG3
Brefeldin A-inhibited guanine nucleotide-exchange protein 3

1

3

High-throughput

0.489

High

1147564

GL8D1
Glycosyltransferase 8 domain-containing protein 1

1

2

High-throughput

0.489

High

1147589

SE1L3
Protein sel-1 homolog 3

1

3

High-throughput

0.489

High

1149860

SCAR3
Scavenger receptor class A member 3

1

7

High-throughput

0.489

High

1159570

TTC27
Tetratricopeptide repeat protein 27

1

5

High-throughput

0.489

High

1162567

TXD11
Thioredoxin domain-containing protein 11

1

12

High-throughput

0.489

High

1165124

PLGT2
Protein O-glucosyltransferase 2

1

4

High-throughput

0.489

High

1175174

TBA1A
Tubulin alpha-1A chain

1

20

High-throughput

0.489

High

1204592

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

2

High-throughput

0.489

High

1205284

DAAF5
Dynein axonemal assembly factor 5

1

1

High-throughput

0.489

High

1218628

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

1

High-throughput

0.489

High

1230039

RPTOR
Regulatory-associated protein of mTOR

1

2

High-throughput

0.489

High

1231658

ABD12
Lysophosphatidylserine lipase ABHD12

1

2

High-throughput

0.489

High

1232004

S35F6
Solute carrier family 35 member F6

1

1

High-throughput

0.489

High

1239990

SUMF1
Formylglycine-generating enzyme

1

4

High-throughput

0.489

High

1240530

ATAD1
Outer mitochondrial transmembrane helix translocase

1

3

High-throughput

0.489

High

1240633

UXS1
UDP-glucuronic acid decarboxylase 1

1

2

High-throughput

0.489

High

1242991

MCU
Calcium uniporter protein, mitochondrial

1

2

High-throughput

0.489

High

1266803

TM9S4
Transmembrane 9 superfamily member 4

1

7

High-throughput

0.489

High

1266840

TM131
Transmembrane protein 131

1

4

High-throughput

0.489

High

1274302

EXT2
Exostosin-2

1

4

High-throughput

0.489

High

1281735

PIGT
GPI transamidase component PIG-T

1

4

High-throughput

0.489

High

1284445

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

3

High-throughput

0.489

High

1287839

COQ8B
Atypical kinase COQ8B, mitochondrial

1

1

High-throughput

0.489

High

1293045

MYO19
Unconventional myosin-XIX

1

2

High-throughput

0.489

High

1297954

H6ST2
Heparan-sulfate 6-O-sulfotransferase 2

1

1

High-throughput

0.489

High

1298480

MBOA7
Lysophospholipid acyltransferase 7

1

2

High-throughput

0.489

High

1300869

PASK
PAS domain-containing serine/threonine-protein kinase

1

3

High-throughput

0.489

High

1301645

JMJD8
JmjC domain-containing protein 8

1

1

High-throughput

0.489

High

1305404

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

1

3

High-throughput

0.489

High

1307286

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

6

High-throughput

0.489

High

1309491

TBA1C
Tubulin alpha-1C chain

1

20

High-throughput

0.489

High

1309845

CSTN3
Calsyntenin-3

1

14

High-throughput

0.489

High

1313602

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

6

High-throughput

0.489

High

1318303

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

6

High-throughput

0.489

High

1327029

ADA19
Disintegrin and metalloproteinase domain-containing protein 19

1

15

High-throughput

0.489

High

1329619

SPNS1
Protein spinster homolog 1

1

2

High-throughput

0.489

High

1329620

SEM6B
Semaphorin-6B

1

11

High-throughput

0.489

High

1329622

TOR3A
Torsin-3A

1

8

High-throughput

0.489

High

1329623

TBB1
Tubulin beta-1 chain

1

20

High-throughput

0.489

High

1329628

CHSTC
Carbohydrate sulfotransferase 12

1

2

High-throughput

0.489

High

1329630

ABCF3
ATP-binding cassette sub-family F member 3

1

1

High-throughput

0.489

High

1329634

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

1

4

High-throughput

0.489

High

1329635

SUN2
SUN domain-containing protein 2

1

2

High-throughput

0.489

High

1329636

PLXA1
Plexin-A1

1

12

High-throughput

0.489

High

1329639

MA2B2
Epididymis-specific alpha-mannosidase

1

7

High-throughput

0.489

High

1329640

TMED5
Transmembrane emp24 domain-containing protein 5

1

11

High-throughput

0.489

High

1329641

LOXL2
Lysyl oxidase homolog 2

1

10

High-throughput

0.489

High

1329644

AGRG1
Adhesion G-protein coupled receptor G1

1

7

High-throughput

0.489

High

1329645

COX11
Cytochrome c oxidase assembly protein COX11, mitochondrial

1

1

High-throughput

0.489

High

1289554

HOOK2
Protein Hook homolog 2

1

2

High-throughput

0.464

High

888995

KR103
Keratin-associated protein 10-3

1

5

High-throughput

0.439

High

165047

SC16A
Protein transport protein Sec16A

1

4

High-throughput

0.437

High

723716

HXD13
Homeobox protein Hox-D13

1

1

High-throughput

0.437

High

1329621

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

1

1

High-throughput

0.437

High

1244947

TOIP2
Torsin-1A-interacting protein 2

1

1

High-throughput

0.407

High

1266678

SMG7
Nonsense-mediated mRNA decay factor SMG7

3

0

High-throughput

0.347

High

1259750

ABHD3
Phospholipase ABHD3

2

0

High-throughput

0.318

High

64447

RTL8C
Retrotransposon Gag-like protein 8C

1

0

High-throughput

0.279

Low

149921

RFXK
DNA-binding protein RFXANK

1

0

High-throughput

0.279

Low

176641

FANCA
Fanconi anemia group A protein

1

0

High-throughput

0.279

Low

195937

TTI1
TELO2-interacting protein 1 homolog

1

0

High-throughput

0.279

Low

674624

ACHA5
Neuronal acetylcholine receptor subunit alpha-5

1

0

High-throughput

0.279

Low

881678

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.279

Low

953179

CCZ1B
Vacuolar fusion protein CCZ1 homolog B

1

0

High-throughput

0.279

Low

968917

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.279

Low

1075084

MARE2
Microtubule-associated protein RP/EB family member 2

1

0

High-throughput

0.279

Low

1099393

T132A
Transmembrane protein 132A

1

0

High-throughput

0.279

Low

1148334

INT3
Integrator complex subunit 3

1

0

High-throughput

0.279

Low

1162206

BRAT1
BRCA1-associated ATM activator 1

1

0

High-throughput

0.279

Low

1217904

MISP
Mitotic interactor and substrate of PLK1

1

0

High-throughput

0.279

Low

1283888

TTC17
Tetratricopeptide repeat protein 17

1

0

High-throughput

0.279

Low

1328346

F234A
Protein FAM234A

1

0

High-throughput

0.279

Low

1329624

SG196
Protein O-mannose kinase

1

0

High-throughput

0.279

Low

1329629

OSTC
Oligosaccharyltransferase complex subunit OSTC

1

0

High-throughput

0.279

Low

1329631

CLN6
Ceroid-lipofuscinosis neuronal protein 6

1

0

High-throughput

0.279

Low

1329633

SELN
Selenoprotein N

1

0

High-throughput

0.279

Low

1329642

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024