HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: MAPK5 (Q8IW41)
MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (MAPKAP-K5) (MAPKAPK-5) (MK-5) (MK5) (EC 2.7.11.1) (p38-regulated/activated protein kinase) (PRAK)
Gene: MAPKAPK5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 473
+	At
		965291 14332_ARATH (4-244): 1.39e-141: 398: 61.32		CDPK1_ARATH (2-473): 6.05e-131: 393: 24.35
+	At
		802001 14334_ARATH (4-244): 5e-140: 395: 60.91		CDPK1_ARATH (2-473): 6.05e-131: 393: 24.35
+	At
		788694 14335_ARATH (3-244): 5.67e-136: 385: 59.02		CDPK1_ARATH (2-473): 6.05e-131: 393: 24.35
+	Hs
		909531 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KCC2G_HUMAN (7-467): 7.25e-120: 363: 22.59
+	Hs
		904531 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KCC2G_HUMAN (7-467): 7.25e-120: 363: 22.59
+	Hs
		981988 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		KCC2G_HUMAN (7-467): 7.25e-120: 363: 22.59
+	Hs
		909532 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KCC2D_HUMAN (7-399): 9.62e-113: 343: 29.28
+	Hs
		904532 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KCC2D_HUMAN (7-399): 9.62e-113: 343: 29.28
+	Hs
		683326 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		KCC2G_HUMAN (7-467): 7.25e-120: 363: 22.59
+	Mm
		659446 1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59		KCC2B_MOUSE (7-467): 1.78e-119: 361: 22.88
+	Mm
		926819 1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59		KCC2D_MOUSE (7-399): 9.62e-113: 343: 29.28
+	Hs
		909811 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		DCLK2_HUMAN (8-312): 5.95e-47: 175: 33.33
+	Hs
		904852 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		DCLK2_HUMAN (8-312): 5.95e-47: 175: 33.33
+	Hs
		982272 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		DCLK2_HUMAN (8-312): 5.95e-47: 175: 33.33
+	Hs
		909590 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KS6A2_HUMAN (28-304): 3.48e-20: 95.9: 29.49
+	Hs
		683540 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		DCLK2_HUMAN (8-312): 5.95e-47: 175: 33.33
+	Hs
		904590 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KS6A1_HUMAN (12-293): 1.61e-19: 93.6: 27.10
+	Hs
		982035 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		KS6A1_HUMAN (12-293): 1.61e-19: 93.6: 27.10
+	Hs
		683368 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		KS6A1_HUMAN (12-293): 1.61e-19: 93.6: 27.10
+	Mm
		926837 1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59		KS6A5_MOUSE (28-293): 4.28e-19: 92.4: 28.21