HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: TET1 (Q8NFU7)
Methylcytosine dioxygenase TET1 (EC 1.14.11.80) (CXXC-type zinc finger protein 6) (Leukemia-associated protein with a CXXC domain) (Ten-eleven translocation 1 gene protein)
Gene: TET1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 247 Hs			1 2136
+	Hs
		909832 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		TET1_HUMAN (1-2136): 0: 3431: 100.00
+	Hs
		982300 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		TET1_HUMAN (1-2136): 0: 3431: 100.00
+	Hs
		647124 1433T_HUMAN (2-245): 5.53e-105: 305: 70.33		TET1_HUMAN (1-2136): 0: 3431: 100.00
+	Hs
		909681 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		TET2_HUMAN (1910-2136): 7.82e-48: 191: 37.45
+	Hs
		904716 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		TET2_HUMAN (1910-2136): 7.82e-48: 191: 37.45
+	Hs
		982143 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		TET2_HUMAN (1910-2136): 7.82e-48: 191: 37.45
+	Hs
		683446 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		TET2_HUMAN (1910-2136): 7.82e-48: 191: 37.45
+	Hs
		927169 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		TET2_HUMAN (1910-2136): 7.82e-48: 191: 37.45
+	Hs
		647002 1433T_HUMAN (2-245): 5.53e-105: 305: 70.33		TET2_HUMAN (1910-2136): 7.82e-48: 191: 37.45
+	Hs
		684120 1433S_HUMAN (2-245): 1.86e-98: 289: 65.16		TET2_HUMAN (1910-2136): 7.82e-48: 191: 37.45