HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.735

Property	Details
Experiments	17353931, 33961781, 35271311, 36931259, 15324660, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 1356
+	Hs
		909852 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		909853 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		PAR3L_HUMAN (1-1354): 5.88e-101: 352: 32.37
+	Mm
		905360 1433G_MOUSE (1-247): 3.15e-139: 392: 100.00		PAR3L_MOUSE (1-1354): 9.31e-103: 357: 32.03
+	Hs
		904907 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		PAR3L_HUMAN (1-1354): 5.88e-101: 352: 32.37
+	Dm
		955046 1433E_DROME (1-243): 1.58e-140: 396: 63.37		Q9VX75_DROME (1-1082): 3.49e-78: 286: 21.87
+	Dm
		954995 1433E_DROME (1-243): 1.58e-140: 396: 63.37		Q0KHR3_DROME (42-1082): 6.25e-62: 235: 20.76
+	Rn
		910361 1433E_RAT (1-244): 2.02e-141: 398: 63.53		RIMS1_RAT (314-947): 2.11e-50: 198: 17.14
+	Rn
		935727 1433F_RAT (1-246): 1.51e-136: 385: 86.99		RIMS1_RAT (314-947): 2.11e-50: 198: 17.14
+	Hs
		904684 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		MAGI3_HUMAN (61-1272): 3.28e-32: 139: 10.65
+	Mm
		910260 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98
+	Mm
		905344 1433G_MOUSE (1-247): 3.15e-139: 392: 100.00		DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98
+	Hs
		280039 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		MPDZ_HUMAN (446-543): 1.36e-20: 101: 40.82
+	Mm
		905355 1433G_MOUSE (1-247): 3.15e-139: 392: 100.00		LNX2_MOUSE (15-361): 1.42e-19: 97: 11.11
+	Hs
		909498 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		904503 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		905015 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16
+	Hs
		904891 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		INADL_HUMAN (28-397): 1.09e-15: 85.1: 11.14
+	Mm
		250604 1433G_MOUSE (1-247): 3.15e-139: 392: 100.00		LNX1_MOUSE (130-385): 1.31e-14: 80.8: 15.33
+	Hs
		904480 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06
+	Hs
		904552 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75