HitPredict

Interactor 1: HMGB3 (O15347)
High mobility group protein B3 (High mobility group protein 2a) (HMG-2a) (High mobility group protein 4) (HMG-4)
Gene: HMGB3

Interactor 2: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 34349018, 30021884
Identification Methods cross-linking study, proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HMG_box~HMG_box, HMG_box~HMG_box_2, HMG_box_2~HMG_box_2
Common GO terms GO:0000400 - four-way junction DNA binding
GO:0003690 - double-stranded DNA binding
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0006310 - DNA recombination
and 4 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 200
Hs

1 215
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024