HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: EDC3 (Q96F86)
Enhancer of mRNA-decapping protein 3 (LSM16 homolog) (YjeF N-terminal domain-containing protein 2) (YjeF_N2) (hYjeF_N2) (YjeF domain-containing protein 1)
Gene: EDC3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.748

Property	Details
Experiments	29395067, 17353931, 33961781, 35271311, 36931259, 15324660, 28514442
Identification Methods	proximity labelling technology, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 247 Hs			1 508
+	Hs
		909901 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		EDC3_HUMAN (1-508): 0: 846: 100.00
+	Hs
		982373 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		EDC3_HUMAN (1-508): 0: 846: 100.00
+	Mm
		910312 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		EDC3_MOUSE (1-508): 0: 826: 95.67
+	Hs
		683616 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		EDC3_HUMAN (1-508): 0: 846: 100.00
+	Hs
		927395 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		EDC3_HUMAN (1-508): 0: 846: 100.00
+	Hs
		647183 1433T_HUMAN (2-245): 5.53e-105: 305: 70.33		EDC3_HUMAN (1-508): 0: 846: 100.00
+	Hs
		684260 1433S_HUMAN (2-245): 1.86e-98: 289: 65.16		EDC3_HUMAN (1-508): 0: 846: 100.00