HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33961781, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 669
+	Hs
		165763 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		N4BP3_HUMAN (17-640): 5.23e-34: 139: 27.16
+	Hs
		905298 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		MTCL1_HUMAN (56-644): 5.72e-34: 141: 14.24
+	Mm
		910338 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		TSC1_MOUSE (48-630): 3.36e-32: 135: 13.67
+	Hs
		165762 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		N4BP3_HUMAN (17-640): 5.23e-34: 139: 27.16
+	Hs
		165766 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		N4BP3_HUMAN (17-640): 5.23e-34: 139: 27.16
+	Hs
		909488 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		CGNL1_HUMAN (321-645): 5.23e-13: 74.7: 21.88
+	Hs
		909555 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Mm
		93548 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		DESP_MOUSE (337-641): 2.9e-11: 69.3: 18.65
+	Hs
		728460 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MYH11_HUMAN (141-564): 3.93e-11: 68.9: 11.53
+	Hs
		904495 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		CGNL1_HUMAN (321-645): 5.23e-13: 74.7: 21.88
+	Hs
		909658 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MRCKA_HUMAN (328-609): 6.79e-09: 61.6: 11.68
+	Hs
		725130 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MYH10_HUMAN (321-640): 8.77e-09: 61.2: 18.79
+	Hs
		981958 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		CGNL1_HUMAN (321-645): 5.23e-13: 74.7: 21.88
+	Hs
		982007 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		904690 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		MRCKA_HUMAN (328-609): 6.79e-09: 61.6: 11.68
+	Hs
		725128 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		MYH10_HUMAN (321-640): 8.77e-09: 61.2: 18.79
+	Hs
		728471 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		MYH11_HUMAN (141-564): 3.93e-11: 68.9: 11.53
+	Hs
		982032 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		982126 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		982116 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		MRCKA_HUMAN (328-609): 6.79e-09: 61.6: 11.68