HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: LATS2 (Q9NRM7)
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)
Gene: LATS2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.629

Property	Details
Experiments	28205554, 21118956
Identification Methods	fluorescent resonance energy transfer, affinity chromatography technology, enzymatic study
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 1088
+	Hs
		325680 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325678 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325701 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Zm
		45993 B6SRI4_MAIZE (2-245): 2.63e-140: 395: 60.16		A0A1Q0ZG94_MAIZE (269-1023): 3.34e-169: 533: 22.75
+	Hs
		910180 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ST38L_HUMAN (592-1051): 1.3e-146: 448: 41.30
+	Hs
		904584 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		STK38_HUMAN (583-1065): 5.24e-146: 447: 40.58
+	Hs
		681770 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		AKT1_HUMAN (532-1043): 2.2e-141: 435: 22.16
+	Hs
		681766 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		AKT1_HUMAN (532-1043): 2.2e-141: 435: 22.16
+	Hs
		909458 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KPCE_HUMAN (554-1010): 1.06e-129: 413: 29.92
+	Hs
		568616 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		KAPCA_HUMAN (635-1024): 1.31e-133: 410: 31.73
+	At
		788319 14331_ARATH (4-244): 4.02e-141: 397: 59.67		KPK1_ARATH (543-1065): 2.94e-132: 411: 25.42
+	Hs
		904456 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KPCE_HUMAN (554-1010): 1.06e-129: 413: 29.92
+	Hs
		909658 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MRCKA_HUMAN (656-1007): 6.11e-76: 277: 41.23
+	Hs
		850630 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KS6A3_HUMAN (519-990): 8.69e-81: 281: 19.63
+	Hs
		904590 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Hs
		904690 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		MRCKA_HUMAN (656-1007): 6.11e-76: 277: 41.23
+	Hs
		850642 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		KS6A3_HUMAN (519-990): 8.69e-81: 281: 19.63
+	Hs
		982035 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Hs
		982116 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		MRCKA_HUMAN (656-1007): 6.11e-76: 277: 41.23
+	Hs
		909524 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		ROCK1_HUMAN (640-1008): 1.28e-70: 260: 38.77