HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.50	0.506

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 2610
+	Hs
		910149 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Mm
		808343 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		NEDD4_MOUSE (2258-2608): 9.66e-121: 407: 19.89
+	Rn
		910358 1433E_RAT (1-244): 2.02e-141: 398: 63.53		NEDD4_RAT (2258-2608): 4.01e-119: 403: 20.11
+	Mm
		93264 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		E9PXB7_MOUSE (2255-2608): 3.94e-119: 401: 21.67
+	Hs
		909930 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		NED4L_HUMAN (2255-2608): 4.26e-117: 399: 21.67
+	Mm
		910302 1433E_MOUSE (1-244): 2.02e-141: 398: 63.53		NED4L_MOUSE (2255-2608): 2.21e-116: 398: 21.67
+	Rn
		905367 1433G_RAT (1-247): 3.15e-139: 392: 100.00		NEDD4_RAT (2258-2608): 4.01e-119: 403: 20.11
+	Mm
		93263 1433G_MOUSE (1-247): 3.15e-139: 392: 100.00		E9PXB7_MOUSE (2255-2608): 3.94e-119: 401: 21.67
+	Hs
		905007 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		NED4L_HUMAN (2255-2608): 4.26e-117: 399: 21.67
+	Hs
		904987 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		ITCH_HUMAN (2234-2608): 3.18e-117: 398: 21.88
+	Rn
		935725 1433F_RAT (1-246): 1.51e-136: 385: 86.99		NEDD4_RAT (2258-2608): 4.01e-119: 403: 20.11
+	Hs
		982400 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		NED4L_HUMAN (2255-2608): 4.26e-117: 399: 21.67
+	Hs
		125318 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		909564 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03
+	Hs
		904561 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03
+	Hs
		982011 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03
+	Hs
		909468 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		UBE3A_HUMAN (2406-2607): 5.17e-25: 116: 34.95
+	Hs
		904471 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		UBE3A_HUMAN (2406-2607): 5.17e-25: 116: 34.95
+	At
		788566 14333_ARATH (1-244): 4.4e-142: 400: 61.79		UPL2_ARATH (2424-2604): 7.84e-20: 100: 34.60
+	Mm
		935540 1433F_MOUSE (1-246): 1.51e-136: 385: 86.99		UBE3C_MOUSE (2405-2610): 3.46e-22: 107: 32.37