HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: EXO1 (Q9UQ84)
Exonuclease 1 (hExo1) (EC 3.1.-.-) (Exonuclease I) (hExoI)
Gene: EXO1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.50	0.629

Property	Details
Experiments	35271311, 36931259, 22222486, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 247 Hs			1 846
+	Hs
		910169 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		EXO1_HUMAN (1-846): 0: 1208: 100.00
+	Hs
		982630 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		EXO1_HUMAN (1-846): 0: 1208: 100.00
+	Hs
		683822 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		EXO1_HUMAN (1-846): 0: 1208: 100.00
+	Hs
		927667 1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59		EXO1_HUMAN (1-846): 0: 1208: 100.00
+	Hs
		647387 1433T_HUMAN (2-245): 5.53e-105: 305: 70.33		EXO1_HUMAN (1-846): 0: 1208: 100.00
+	Hs
		684402 1433S_HUMAN (2-245): 1.86e-98: 289: 65.16		EXO1_HUMAN (1-846): 0: 1208: 100.00
+	Hs
		764357 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		FEN1_HUMAN (1-365): 6e-128: 390: 25.93
+	Hs
		904621 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		GEN_HUMAN (1-338): 5.74e-91: 309: 16.77
+	Hs
		982056 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		GEN_HUMAN (1-338): 5.74e-91: 309: 16.77
+	At
		965323 14332_ARATH (4-244): 1.39e-141: 398: 61.32		UVH3_ARATH (1-109): 3.08e-32: 137: 23.85