Interactor 1: IRAK1 (P51617)
Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)
Gene: IRAK1
Interactor 2: UN5CL (Q8IV45)
UNC5C-like protein (Protein unc-5 homolog C-like) (ZU5 and death domain-containing protein)
Gene: UNC5CL
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22158417 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Death~Death, Death~ZU5 |
| Common GO terms | GO:0005829 - cytosol GO:0043123 - positive regulation of canonical NF-kappaB signal transduction |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
