Protein: EXOS6
Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog) (hMtr3) (p11)

Gene: EXOS6, EXOSC6
Organism: Homo sapiens
Interactions: 110
UniProt ID: Q5RKV6

Gene Ontology (top 5):
GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1063723

EXOS7
Exosome complex component RRP42

7

17

Small-scale

0.961

High

1130069

EXOS1
Exosome complex component CSL4

6

20

Small-scale

0.948

High

1130057

EXOS4
Exosome complex component RRP41

4

18

Small-scale

0.909

High

1046290

EXOS2
Exosome complex component RRP4

4

20

Small-scale

0.892

High

1130058

EXOS5
Exosome complex component RRP46

3

19

High-throughput

0.871

High

1130037

DI3L1
DIS3-like exonuclease 1

3

20

Small-scale

0.861

High

1130042

EXOS8
Exosome complex component RRP43

3

19

Small-scale

0.828

High

986681

EXOS9
Exosome complex component RRP45

2

17

High-throughput

0.789

High

1130059

EXOS3
Exosome complex component RRP40

6

13

Small-scale

0.735

High

966418

EXOSX
Exosome complex component 10

4

11

Small-scale

0.674

High

1130047

MPH6
M-phase phosphoprotein 6

3

8

Small-scale

0.660

High

1085764

IF16
Gamma-interferon-inducible protein 16

3

7

High-throughput

0.656

High

1047021

C1D
Nuclear nucleic acid-binding protein C1D

2

5

High-throughput

0.628

High

1130025

EXOS6
Exosome complex component MTR3

1

19

High-throughput

0.621

High

1130071

RBM7
RNA-binding protein 7

2

7

High-throughput

0.611

High

1130070

HBS1L
HBS1-like protein

2

6

Small-scale

0.595

High

786962

MTREX
Exosome RNA helicase MTR4

2

16

High-throughput

0.586

High

255848

OBSL1
Obscurin-like protein 1

2

4

High-throughput

0.584

High

779552

CCNF
Cyclin-F

2

1

High-throughput

0.584

High

1130060

ANLN
Anillin

2

4

High-throughput

0.584

High

336521

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.536

High

781755

MNDA
Myeloid cell nuclear differentiation antigen

1

7

High-throughput

0.536

High

1041739

CUL3
Cullin-3

1

2

High-throughput

0.536

High

1130038

PHF10
PHD finger protein 10

1

7

High-throughput

0.536

High

1130052

AICDA
Single-stranded DNA cytosine deaminase

1

7

Small-scale

0.536

High

529231

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

850934

HDGF
Hepatoma-derived growth factor

1

0

High-throughput

0.513

High

571149

EGLN
Endoglin

1

1

High-throughput

0.489

High

167696

LSM1
U6 snRNA-associated Sm-like protein LSm1

1

7

High-throughput

0.481

High

321408

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

8

High-throughput

0.481

High

510023

ERR1
Steroid hormone receptor ERR1

1

13

High-throughput

0.481

High

644269

TTP
mRNA decay activator protein ZFP36

1

1

High-throughput

0.481

High

827416

EFTU
Elongation factor Tu, mitochondrial

1

4

High-throughput

0.481

High

951991

SRSF3
Serine/arginine-rich splicing factor 3

1

2

High-throughput

0.481

High

990099

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

High-throughput

0.481

High

1032103

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

2

High-throughput

0.481

High

1130033

DCP1B
mRNA-decapping enzyme 1B

1

1

High-throughput

0.481

High

1130034

XRN1
5'-3' exoribonuclease 1

1

2

High-throughput

0.481

High

1130051

RM04
Large ribosomal subunit protein uL4m

1

1

High-throughput

0.481

High

1130056

RENT2
Regulator of nonsense transcripts 2

1

2

High-throughput

0.481

High

1130066

LSM7
U6 snRNA-associated Sm-like protein LSm7

1

8

High-throughput

0.481

High

117413

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

1

High-throughput

0.479

High

122811

MEN1
Menin

1

5

High-throughput

0.479

High

125511

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

4

High-throughput

0.479

High

160609

AURKA
Aurora kinase A

1

1

High-throughput

0.479

High

182787

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.479

High

237226

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

5

High-throughput

0.479

High

294915

RECQ4
ATP-dependent DNA helicase Q4

1

7

High-throughput

0.479

High

312618

ARI2
E3 ubiquitin-protein ligase ARIH2

1

4

High-throughput

0.479

High

322725

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

9

High-throughput

0.479

High

346987

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.479

High

442218

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

11

High-throughput

0.479

High

781382

BCL6
B-cell lymphoma 6 protein

1

1

High-throughput

0.479

High

818126

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.479

High

841230

CDK7
Cyclin-dependent kinase 7

1

1

High-throughput

0.479

High

857002

THOP1
Thimet oligopeptidase

1

5

High-throughput

0.479

High

877757

FOXA1
Hepatocyte nuclear factor 3-alpha

1

3

High-throughput

0.479

High

908664

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.479

High

917398

H4
Histone H4

1

1

High-throughput

0.479

High

918423

H2B1C
Histone H2B type 1-C/E/F/G/I

1

2

High-throughput

0.479

High

952384

H33
Histone H3.3

1

2

High-throughput

0.479

High

1022114

NFX1
Transcriptional repressor NF-X1

1

4

High-throughput

0.479

High

1035810

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

1064384

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.479

High

1080016

EZH2
Histone-lysine N-methyltransferase EZH2

1

4

High-throughput

0.479

High

1116309

LARP7
La-related protein 7

1

3

High-throughput

0.479

High

1130026

ZCHC8
Zinc finger CCHC domain-containing protein 8

1

5

High-throughput

0.479

High

1130027

GGYF2
GRB10-interacting GYF protein 2

1

5

High-throughput

0.479

High

1130029

MOB3C
MOB kinase activator 3C

1

1

High-throughput

0.479

High

1130030

ZCH18
Zinc finger CCCH domain-containing protein 18

1

7

High-throughput

0.479

High

1130035

BICD2
Protein bicaudal D homolog 2

1

4

High-throughput

0.479

High

1130036

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

5

High-throughput

0.479

High

1130039

ESR2
Estrogen receptor beta

1

13

High-throughput

0.479

High

1130040

KAT6A
Histone acetyltransferase KAT6A

1

7

High-throughput

0.479

High

1130041

FBXW7
F-box/WD repeat-containing protein 7

1

1

High-throughput

0.479

High

1130044

DDRGK
DDRGK domain-containing protein 1

1

5

High-throughput

0.479

High

1130046

RANB9
Ran-binding protein 9

1

1

High-throughput

0.479

High

1130048

ANM1
Protein arginine N-methyltransferase 1

1

3

High-throughput

0.479

High

1130049

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

1

High-throughput

0.479

High

1130050

CP250
Centrosome-associated protein CEP250

1

2

High-throughput

0.479

High

1130063

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

6

High-throughput

0.479

High

1130064

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1130068

FZR1
Fizzy-related protein homolog

1

6

High-throughput

0.479

High

69241

MI4GD
MIF4G domain-containing protein

1

0

High-throughput

0.460

High

214949

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.460

High

313136

MOCS3
Adenylyltransferase and sulfurtransferase MOCS3

1

0

High-throughput

0.460

High

594552

PSB1
Proteasome subunit beta type-1

1

0

High-throughput

0.460

High

1130032

CHSS2
Chondroitin sulfate synthase 2

1

0

High-throughput

0.460

High

1130053

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.460

High

1130061

MA2C1
Alpha-mannosidase 2C1

1

0

High-throughput

0.460

High

1130062

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

1

0

High-throughput

0.460

High

1130072

RT18B
Small ribosomal subunit protein mS40

1

0

High-throughput

0.460

High

242100

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

632295

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.458

High

742337

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

1130043

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

402124

JUN
Transcription factor Jun

1

4

High-throughput

0.445

High

497154

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.445

High

1039619

SNW1
SNW domain-containing protein 1

1

3

High-throughput

0.445

High

1130055

LN28A
Protein lin-28 homolog A

1

6

High-throughput

0.445

High

1130045

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

1

High-throughput

0.439

High

1130028

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1130054

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.437

High

1130065

DS13B
Dual specificity protein phosphatase 13B

1

1

High-throughput

0.437

High

1130067

HECD1
E3 ubiquitin-protein ligase HECTD1

1

10

High-throughput

0.437

High

968601

TAGL
Transgelin

1

2

High-throughput

0.407

High

1130031

MF2L2
Probable guanine nucleotide exchange factor MCF2L2

2

0

High-throughput

0.298

High

1057818

GSE1
Genetic suppressor element 1

1

0

High-throughput

0.251

Low

596003

EFNA1
Ephrin-A1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024