HitPredict

Interactor 1: PP1A (P62137)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: Ppp1ca

Interactor 2: IASPP (Q5I1X5)
RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (NFkB-interacting protein 1) (PPP1R13B-like protein)
Gene: Ppp1r13l

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	29669786, unassigned3533
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 330 Mm			1 824
+	Hs
		906042 PP1A_HUMAN (1-330): 0: 614: 99.70		IASPP_HUMAN (1-821): 8.79e-95: 317: 88.24
+	Hs
		905884 PP1A_HUMAN (1-330): 0: 614: 99.70		ASPP2_HUMAN (5-824): 2.37e-68: 248: 21.45
+	Mm
		93784 PP1A_MOUSE (1-330): 0: 614: 100.00		E9QJU8_MOUSE (5-824): 4.06e-68: 247: 22.67
+	Hs
		905849 PP1A_HUMAN (1-330): 0: 614: 99.70		Q05BL1_HUMAN (5-824): 2.41e-65: 238: 21.45
+	Mm
		906278 PP1A_MOUSE (1-330): 0: 614: 100.00		ASPP1_MOUSE (5-824): 3.85e-64: 235: 24.61
+	Hs
		737795 PP1G_HUMAN (1-330): 0: 579: 90.36		ASPP2_HUMAN (5-824): 2.37e-68: 248: 21.45
+	Hs
		737760 PP1G_HUMAN (1-330): 0: 579: 90.36		Q05BL1_HUMAN (5-824): 2.41e-65: 238: 21.45
+	Hs
		906000 PP1A_HUMAN (1-330): 0: 614: 99.70		PPR27_HUMAN (617-733): 7.3e-26: 105: 32.20
+	Hs
		906079 PP1A_HUMAN (1-330): 0: 614: 99.70		PP16A_HUMAN (636-734): 1.05e-18: 92.5: 29.29
+	Hs
		161347 PP1A_HUMAN (1-330): 0: 614: 99.70		MYPT1_HUMAN (609-756): 1.48e-16: 86.7: 27.82
+	Hs
		906099 PP1A_HUMAN (1-330): 0: 614: 99.70		PP16B_HUMAN (642-734): 9.22e-17: 86.3: 29.03
+	Mm
		906366 PP1A_MOUSE (1-330): 0: 614: 100.00		MYPT1_MOUSE (609-756): 6.92e-16: 84.4: 28.48
+	Hs
		906081 PP1A_HUMAN (1-330): 0: 614: 99.70		ASPP1_HUMAN (1-637): 3.51e-12: 72.5: 9.47
+	Mm
		906293 PP1A_MOUSE (1-330): 0: 614: 100.00		MYPT2_MOUSE (636-747): 1.09e-11: 70.9: 27.19
+	Hs
		225132 PP1A_HUMAN (1-330): 0: 614: 99.70		MYPT2_HUMAN (636-742): 7.53e-11: 68.2: 26.61
+	Mm
		906252 PP1A_MOUSE (1-330): 0: 614: 100.00		PP12C_MOUSE (629-733): 5.96e-10: 65.1: 25.46
+	Hs
		906116 PP1A_HUMAN (1-330): 0: 614: 99.70		PP12C_HUMAN (629-731): 5.61e-09: 61.7: 25.93
+	Hs
		161322 PP1G_HUMAN (1-330): 0: 579: 90.36		MYPT1_HUMAN (609-756): 1.48e-16: 86.7: 27.82
+	Mm
		926555 PP1G_MOUSE (1-330): 0: 579: 90.36		MYPT1_MOUSE (609-756): 6.92e-16: 84.4: 28.48
+	Hs
		225129 PP1G_HUMAN (1-330): 0: 579: 90.36		MYPT2_HUMAN (636-742): 7.53e-11: 68.2: 26.61