HitPredict

Interactor 1: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Interactor 2: Q05BL1 (Q05BL1)
TP53BP2 protein
Gene: TP53BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 327 Hs			1 1048
+	Hs
		906447 PP1B_HUMAN (1-327): 0: 597: 100.00		ASPP2_HUMAN (7-1048): 1.52e-161: 508: 99.71
+	Hs
		905849 PP1A_HUMAN (1-326): 0: 576: 88.79		Q05BL1_HUMAN (1-1048): 3.21e-158: 497: 100.00
+	Mm
		93784 PP1A_MOUSE (1-326): 0: 576: 88.49		E9QJU8_MOUSE (7-1048): 3.29e-150: 478: 89.93
+	Hs
		906562 PP1B_HUMAN (1-327): 0: 597: 100.00		ASPP1_HUMAN (10-1048): 1.44e-101: 346: 44.03
+	Mm
		906278 PP1A_MOUSE (1-326): 0: 576: 88.49		ASPP1_MOUSE (10-1048): 2.06e-103: 351: 43.08
+	Hs
		906543 PP1B_HUMAN (1-327): 0: 597: 100.00		IASPP_HUMAN (301-1047): 2.1e-53: 203: 21.33
+	Mm
		906260 PP1A_MOUSE (1-326): 0: 576: 88.49		IASPP_MOUSE (301-1047): 1.69e-56: 212: 20.89
+	Hs
		3260 PP1B_HUMAN (1-327): 0: 597: 100.00		A0A0S2Z4Q8_HUMAN (821-955): 5.61e-51: 179: 34.07
+	Hs
		906517 PP1B_HUMAN (1-327): 0: 597: 100.00		PPR27_HUMAN (840-956): 9.58e-38: 140: 32.20
+	Hs
		906561 PP1B_HUMAN (1-327): 0: 597: 100.00		PP16A_HUMAN (859-957): 8.99e-21: 99.5: 33.33
+	Hs
		906572 PP1B_HUMAN (1-327): 0: 597: 100.00		PP16B_HUMAN (865-957): 1.31e-19: 96.1: 36.56
+	Hs
		161348 PP1B_HUMAN (1-327): 0: 597: 100.00		MYPT1_HUMAN (877-979): 4.12e-16: 85.7: 36.89
+	Gg
		907234 PP1B_CHICK (1-327): 0: 597: 100.00		MYPT1_CHICK (877-979): 6.06e-16: 85.3: 37.86
+	Hs
		906585 PP1B_HUMAN (1-327): 0: 597: 100.00		PP12C_HUMAN (826-954): 9.69e-12: 71.4: 23.88
+	Hs
		225133 PP1B_HUMAN (1-327): 0: 597: 100.00		MYPT2_HUMAN (867-955): 1.87e-11: 70.7: 33.71
+	Hs
		161347 PP1A_HUMAN (1-326): 0: 576: 88.79		MYPT1_HUMAN (877-979): 4.12e-16: 85.7: 36.89
+	Mm
		906366 PP1A_MOUSE (1-326): 0: 576: 88.49		MYPT1_MOUSE (811-979): 8.48e-16: 84.5: 26.74
+	Mm
		906252 PP1A_MOUSE (1-326): 0: 576: 88.49		PP12C_MOUSE (826-956): 9.17e-13: 74.5: 24.27
+	Mm
		906293 PP1A_MOUSE (1-326): 0: 576: 88.49		MYPT2_MOUSE (867-955): 4.18e-12: 72.6: 33.71
+	Hs
		225132 PP1A_HUMAN (1-326): 0: 576: 88.79		MYPT2_HUMAN (867-955): 1.87e-11: 70.7: 33.71