HitPredict

Interactor 1: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Interactor 2: CYTSB (Q5M775)
Cytospin-B (Nuclear structure protein 5) (NSP5) (Sperm antigen HCMOGT-1) (Sperm antigen with calponin homology and coiled-coil domains 1)
Gene: SPECC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 327 Hs			1 1068
+	Hs
		737849 PP1G_HUMAN (1-327): 0: 569: 86.89		CYTSB_HUMAN (1-1068): 5.36e-72: 262: 100.00
+	Hs
		905938 PP1A_HUMAN (1-326): 0: 576: 88.79		SMTL2_HUMAN (624-1067): 1.03e-41: 161: 18.14
+	Hs
		906527 PP1B_HUMAN (1-327): 0: 597: 100.00		MILK2_HUMAN (962-1066): 5.25e-33: 140: 37.74
+	Hs
		521519 PP1B_HUMAN (1-327): 0: 597: 100.00		ACTN1_HUMAN (960-1067): 7.16e-33: 139: 40.37
+	Hs
		528366 PP1A_HUMAN (1-326): 0: 576: 88.79		MYH6_HUMAN (148-986): 1.44e-34: 146: 9.91
+	Mm
		906240 PP1A_MOUSE (1-326): 0: 576: 88.49		MYH6_MOUSE (148-986): 2.06e-34: 145: 9.91
+	Hs
		724747 PP1B_HUMAN (1-327): 0: 597: 100.00		MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16
+	Hs
		724746 PP1A_HUMAN (1-326): 0: 576: 88.79		MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16
+	Hs
		725638 PP1B_HUMAN (1-327): 0: 597: 100.00		ACTN2_HUMAN (963-1066): 3.61e-15: 82.4: 40.95
+	Hs
		724689 PP1G_HUMAN (1-327): 0: 569: 86.89		MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16
+	Hs
		211552 PP1B_HUMAN (1-327): 0: 597: 100.00		ACTN4_HUMAN (963-1066): 6.3e-15: 81.6: 41.91
+	Hs
		906607 PP1B_HUMAN (1-327): 0: 597: 100.00		MYO5C_HUMAN (47-496): 1.63e-12: 74.3: 10.21
+	Hs
		906496 PP1B_HUMAN (1-327): 0: 597: 100.00		CYTSA_HUMAN (1-389): 7.43e-11: 68.7: 7.36
+	Dm
		819254 PP1B_DROME (1-322): 0: 568: 90.37		Q0KI67_DROME (60-626): 6.25e-17: 88.9: 12.48
+	Hs
		725131 PP2AB_HUMAN (8-303): 1.26e-176: 492: 46.13		MYH10_HUMAN (120-977): 3.57e-39: 161: 10.29
+	Hs
		906154 PP1A_HUMAN (1-326): 0: 576: 88.79		MYO5C_HUMAN (47-496): 1.63e-12: 74.3: 10.21
+	Hs
		738064 PP1G_HUMAN (1-327): 0: 569: 86.89		MYO5C_HUMAN (47-496): 1.63e-12: 74.3: 10.21
+	Dm
		1213450 Q8T0U6_DROME (18-322): 0: 550: 91.48		Q8INC3_DROME (81-626): 1.44e-17: 90.8: 13.54
+	Hs
		737866 PP1G_HUMAN (1-327): 0: 569: 86.89		CYTSA_HUMAN (1-389): 7.43e-11: 68.7: 7.36
+	Hs
		724764 PP2AA_HUMAN (8-303): 2.77e-176: 491: 45.79		MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16