HitPredict

Interactor 1: PRS8 (P62195)
26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)
Gene: PSMC5

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned1853
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031410 - cytoplasmic vesicle GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 2527
+	Hs
		1121448 Q53HB3_HUMAN (4-396): 2.75e-139: 406: 46.31		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		798689 PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		3598 A0A140VK70_HUMAN (84-392): 1.21e-115: 345: 56.31		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		913290 PRS10_HUMAN (8-101): 2.13e-10: 64: 10.64		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		816 A0A087X2I1_HUMAN (8-101): 2.4e-10: 63.6: 10.64		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		907187 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		SHOC2_HUMAN (944-1353): 1.23e-60: 222: 22.27