Protein: MCLN3
Mucolipin-3 (Transient receptor potential channel mucolipin 3) (TRPML3)

Gene: MCLN3, MCOLN3
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q8TDD5

Gene Ontology (top 5):
GO:0000421 - autophagosome membrane
GO:0005253 - monoatomic anion channel activity
GO:0005262 - calcium channel activity
GO:0005267 - potassium channel activity
GO:0005272 - sodium channel activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1316534

MCLN2
Mucolipin-2

4

4

High-throughput

0.892

High

1351231

MCLN1
Mucolipin-1

3

4

High-throughput

0.861

High

1351237

KCNQ5
Potassium voltage-gated channel subfamily KQT member 5

3

0

High-throughput

0.816

High

1351229

S12A9
Solute carrier family 12 member 9

3

1

High-throughput

0.667

High

1351236

AT132
Polyamine-transporting ATPase 13A2

3

1

High-throughput

0.667

High

703435

GBRB3
Gamma-aminobutyric acid receptor subunit beta-3

3

0

High-throughput

0.638

High

907823

CLCN7
H(+)/Cl(-) exchange transporter 7

3

0

High-throughput

0.638

High

935692

MFAP3
Microfibril-associated glycoprotein 3

3

0

High-throughput

0.638

High

1023436

AT8B2
Phospholipid-transporting ATPase ID

3

0

High-throughput

0.638

High

1106171

TUSC3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3

3

0

High-throughput

0.638

High

1154812

KCNJ8
ATP-sensitive inward rectifier potassium channel 8

3

0

High-throughput

0.638

High

1294337

TM219
Insulin-like growth factor-binding protein 3 receptor

3

0

High-throughput

0.638

High

1351222

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

3

0

High-throughput

0.638

High

1351223

TTC17
Tetratricopeptide repeat protein 17

3

0

High-throughput

0.638

High

1351224

ASTRA
Protein Aster-A

3

0

High-throughput

0.638

High

1351227

ABCA3
Phospholipid-transporting ATPase ABCA3

3

0

High-throughput

0.638

High

1351228

SGPP1
Sphingosine-1-phosphate phosphatase 1

3

0

High-throughput

0.638

High

1351241

NB5R1
NADH-cytochrome b5 reductase 1

3

0

High-throughput

0.638

High

1351245

DGLA
Diacylglycerol lipase-alpha

3

0

High-throughput

0.638

High

1351246

SNX14
Sorting nexin-14

3

0

High-throughput

0.638

High

137387

BT3A3
Butyrophilin subfamily 3 member A3

2

1

High-throughput

0.628

High

1351214

ST7L
Suppressor of tumorigenicity 7 protein-like

3

1

High-throughput

0.609

High

1351220

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

3

1

High-throughput

0.609

High

1351221

TM131
Transmembrane protein 131

3

2

High-throughput

0.609

High

1351244

DHRS7
Dehydrogenase/reductase SDR family member 7

3

1

High-throughput

0.609

High

907042

CCR6
C-C chemokine receptor type 6

1

1

High-throughput

0.536

High

520936

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

0

High-throughput

0.513

High

61124

T131L
Transmembrane protein 131-like

1

1

High-throughput

0.479

High

933449

S12A2
Solute carrier family 12 member 2

1

1

High-throughput

0.479

High

654992

ITA6
Integrin alpha-6

1

0

High-throughput

0.458

High

1207881

S27A3
Long-chain fatty acid transport protein 3

1

0

High-throughput

0.458

High

1293266

LSR
Lipolysis-stimulated lipoprotein receptor

1

0

High-throughput

0.458

High

1351230

SEM4C
Semaphorin-4C

1

0

High-throughput

0.458

High

1351234

PACC1
Proton-activated chloride channel

1

0

High-throughput

0.458

High

1351238

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.437

High

1309390

SPNS2
Sphingosine-1-phosphate transporter SPNS2

1

0

High-throughput

0.426

High

1351235

ANKH
Mineralization regulator ANKH

1

0

High-throughput

0.426

High

1351243

FLVC2
Choline/ethanolamine transporter FLVCR2

1

0

High-throughput

0.426

High

1131578

MFS10
Major facilitator superfamily domain-containing protein 10

1

2

High-throughput

0.407

High

72668

UPK3L
Uroplakin-3b-like protein 1

3

0

High-throughput

0.347

High

129883

GET1
Guided entry of tail-anchored proteins factor 1

3

0

High-throughput

0.347

High

350394

ABHGA
Phosphatidylserine lipase ABHD16A

3

0

High-throughput

0.347

High

1085349

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

3

0

High-throughput

0.347

High

1276016

D19L4
Probable C-mannosyltransferase DPY19L4

3

0

High-throughput

0.347

High

1294218

GOLI
E3 ubiquitin-protein ligase RNF130

3

0

High-throughput

0.347

High

1351219

DCAKD
Dephospho-CoA kinase domain-containing protein

3

0

High-throughput

0.347

High

1351232

COA1
Cytochrome c oxidase assembly factor 1 homolog

3

0

High-throughput

0.347

High

1351233

TMX4
Thioredoxin-related transmembrane protein 4

3

0

High-throughput

0.347

High

1351239

DJC11
DnaJ homolog subfamily C member 11

3

0

High-throughput

0.347

High

1351242

TM59L
Transmembrane protein 59-like

3

0

High-throughput

0.347

High

1260335

PGAP1
GPI inositol-deacylase

2

0

High-throughput

0.318

High

1351240

IMPA3
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase

2

0

High-throughput

0.318

High

1006573

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.287

High

1351215

PXYP1
2-phosphoxylose phosphatase 1

1

0

High-throughput

0.279

Low

1351226

ACY3
N-acyl-aromatic-L-amino acid amidohydrolase

1

0

High-throughput

0.279

Low

212589

GPAA1
GPI-anchor transamidase component GPAA1

1

0

High-throughput

0.249

Low

1164142

CP51A
Lanosterol 14-alpha demethylase

1

0

High-throughput

0.249

Low

1200408

TM177
Transmembrane protein 177

1

0

High-throughput

0.249

Low

1238356

RETST
All-trans-retinol 13,14-reductase

1

0

High-throughput

0.249

Low

1275377

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

0

High-throughput

0.249

Low

1332873

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.249

Low

1349357

RDH11
Retinol dehydrogenase 11

1

0

High-throughput

0.249

Low

1351216

PIGO
GPI ethanolamine phosphate transferase 3, catalytic subunit

1

0

High-throughput

0.249

Low

1351217

THEM6
Protein THEM6

1

0

High-throughput

0.249

Low

1351218

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.249

Low

1351225

BSCL2
Seipin

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025