Protein: CCR6
C-C chemokine receptor type 6 (C-C CKR-6) (CC-CKR-6) (CCR-6) (Chemokine receptor-like 3) (CKR-L3) (DRY6) (G-protein coupled receptor 29) (GPR-CY4) (GPRCY4) (LARC receptor) (CD antigen CD196)

Gene: CCR6
Organism: Homo sapiens
Interactions: 96
UniProt ID: P51684

Gene Ontology (top 5):
GO:0002407 - dendritic cell chemotaxis
GO:0002523 - leukocyte migration involved in inflammatory response
GO:0004950 - chemokine receptor activity
GO:0005886 - plasma membrane
GO:0006935 - chemotaxis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

907007

CCL20
C-C motif chemokine 20

3

20

Small-scale

0.825

High

133176

QSOX1
Sulfhydryl oxidase 1

1

3

High-throughput

0.625

High

270632

ATP9A
Probable phospholipid-transporting ATPase IIA

2

9

High-throughput

0.601

High

661243

AT2B4
Plasma membrane calcium-transporting ATPase 4

2

20

High-throughput

0.601

High

907013

ITPR3
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3

2

3

High-throughput

0.601

High

907031

AN13A
Ankyrin repeat domain-containing protein 13A

2

3

High-throughput

0.601

High

907055

YIPF3
Protein YIPF3

2

6

High-throughput

0.601

High

141911

PODXL
Podocalyxin

2

0

High-throughput

0.576

High

399673

HMDH
3-hydroxy-3-methylglutaryl-coenzyme A reductase

2

5

High-throughput

0.549

High

907015

YIF1B
Protein YIF1B

2

4

High-throughput

0.549

High

907026

ERMP1
Endoplasmic reticulum metallopeptidase 1

2

4

High-throughput

0.549

High

907032

CERS5
Ceramide synthase 5

2

14

High-throughput

0.549

High

907038

GOGA5
Golgin subfamily A member 5

2

5

High-throughput

0.549

High

184146

RER1
Protein RER1

1

3

High-throughput

0.536

High

252667

TSN3
Tetraspanin-3

1

12

High-throughput

0.536

High

256011

S19A2
Thiamine transporter 1

1

5

High-throughput

0.536

High

320440

TM63A
Mechanosensitive cation channel TMEM63A

1

4

High-throughput

0.536

High

336534

PIGN
GPI ethanolamine phosphate transferase 1

1

14

High-throughput

0.536

High

349396

TSN15
Tetraspanin-15

1

12

High-throughput

0.536

High

354102

CLPT1
Putative lipid scramblase CLPTM1

1

5

High-throughput

0.536

High

419974

B3A2
Anion exchange protein 2

1

3

High-throughput

0.536

High

467245

MDR1
ATP-dependent translocase ABCB1

1

11

High-throughput

0.536

High

624615

SL9A1
Sodium/hydrogen exchanger 1

1

2

High-throughput

0.536

High

907004

AT12A
Potassium-transporting ATPase alpha chain 2

1

17

High-throughput

0.536

High

907008

AT2C1
Calcium-transporting ATPase type 2C member 1

1

20

High-throughput

0.536

High

907009

AT8B2
Phospholipid-transporting ATPase ID

1

20

High-throughput

0.536

High

907010

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

20

High-throughput

0.536

High

907012

ITPR2
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2

1

3

High-throughput

0.536

High

907019

LMBD2
G-protein coupled receptor-associated protein LMBRD2

1

6

High-throughput

0.536

High

907020

MFSD5
Molybdate-anion transporter

1

1

High-throughput

0.536

High

907034

TM87A
Transmembrane protein 87A

1

7

High-throughput

0.536

High

907035

T161B
Transmembrane protein 161B

1

4

High-throughput

0.536

High

907037

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

11

High-throughput

0.536

High

907039

SPPL3
Signal peptide peptidase-like 3

1

4

High-throughput

0.536

High

907040

SPP2B
Signal peptide peptidase-like 2B

1

4

High-throughput

0.536

High

907041

SPP
Signal peptide peptidase

1

4

High-throughput

0.536

High

907042

MCLN3
Mucolipin-3

1

1

High-throughput

0.536

High

907044

LMBR1
Limb region 1 protein homolog

1

2

High-throughput

0.536

High

907051

S29A1
Equilibrative nucleoside transporter 1

1

2

High-throughput

0.536

High

907054

TTYH3
Protein tweety homolog 3

1

3

High-throughput

0.536

High

907058

MCLN1
Mucolipin-1

1

1

High-throughput

0.536

High

907063

SERC1
Serine incorporator 1

1

3

High-throughput

0.536

High

907071

S39AA
Zinc transporter ZIP10

1

8

High-throughput

0.536

High

223715

NDUB3
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

1

3

High-throughput

0.489

High

397675

NU4M
NADH-ubiquinone oxidoreductase chain 4

1

1

High-throughput

0.489

High

665556

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

3

High-throughput

0.489

High

907005

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

1

High-throughput

0.489

High

907016

AG10A
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

7

High-throughput

0.489

High

907017

PIGG
GPI ethanolamine phosphate transferase 2, catalytic subunit

1

14

High-throughput

0.489

High

907018

RRAGB
Ras-related GTP-binding protein B

1

2

High-throughput

0.489

High

907021

RINT1
RAD50-interacting protein 1

1

5

High-throughput

0.489

High

907022

MBOA5
Lysophospholipid acyltransferase 5

1

7

High-throughput

0.489

High

907023

LCLT1
Lysocardiolipin acyltransferase 1

1

6

High-throughput

0.489

High

907024

CERS6
Ceramide synthase 6

1

14

High-throughput

0.489

High

907025

DYM
Dymeclin

1

5

High-throughput

0.489

High

907029

ZDH13
Palmitoyltransferase ZDHHC13

1

8

High-throughput

0.489

High

907030

K2013
Uncharacterized protein KIAA2013

1

4

High-throughput

0.489

High

907033

FITM2
Acyl-coenzyme A diphosphatase FITM2

1

1

High-throughput

0.489

High

907036

MFSD8
Major facilitator superfamily domain-containing protein 8

1

5

High-throughput

0.489

High

907043

CHPT1
Cholinephosphotransferase 1

1

4

High-throughput

0.489

High

907045

ALG3
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

1

1

High-throughput

0.489

High

907046

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

20

High-throughput

0.489

High

907048

TV23C
Golgi apparatus membrane protein TVP23 homolog C

1

2

High-throughput

0.489

High

907049

RN170
E3 ubiquitin-protein ligase RNF170

1

1

High-throughput

0.489

High

907052

PTSS2
Phosphatidylserine synthase 2

1

8

High-throughput

0.489

High

907056

DERL2
Derlin-2

1

2

High-throughput

0.489

High

907057

ELOV4
Very long chain fatty acid elongase 4

1

3

High-throughput

0.489

High

907059

AT133
Polyamine-transporting ATPase 13A3

1

20

High-throughput

0.489

High

907060

RRAGC
Ras-related GTP-binding protein C

1

2

High-throughput

0.489

High

907061

AT131
Endoplasmic reticulum transmembrane helix translocase

1

20

High-throughput

0.489

High

907062

MRS2
Magnesium transporter MRS2 homolog, mitochondrial

1

1

High-throughput

0.489

High

907064

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

4

High-throughput

0.489

High

907065

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

2

High-throughput

0.489

High

907066

RMND1
Required for meiotic nuclear division protein 1 homolog

1

1

High-throughput

0.489

High

907068

ERAP1
Endoplasmic reticulum aminopeptidase 1

1

3

High-throughput

0.489

High

907069

IPO11
Importin-11

1

13

High-throughput

0.489

High

907072

TMCO1
Calcium load-activated calcium channel

1

2

High-throughput

0.489

High

907073

DOLK
Dolichol kinase

1

2

High-throughput

0.489

High

907074

T184B
Transmembrane protein 184B

1

1

High-throughput

0.489

High

184540

DFB4A
Defensin beta 4A

1

1

Small-scale

0.479

High

607557

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

15

High-throughput

0.445

High

907011

S39A6
Zinc transporter ZIP6

1

8

High-throughput

0.445

High

907014

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

15

High-throughput

0.445

High

907050

P2RX4
P2X purinoceptor 4

1

1

High-throughput

0.445

High

506582

GPHRB
Golgi pH regulator B

1

9

High-throughput

0.437

High

85355

GPHRA
Golgi pH regulator A

1

9

High-throughput

0.407

High

295913

SC5D
Lathosterol oxidase

1

3

High-throughput

0.407

High

611043

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

16

High-throughput

0.407

High

907028

GP180
Integral membrane protein GPR180

1

3

High-throughput

0.407

High

907047

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

1

High-throughput

0.407

High

357854

CYB
Cytochrome b

1

0

High-throughput

0.279

Low

907006

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

0

High-throughput

0.279

Low

907053

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.279

Low

907070

POMT2
Protein O-mannosyl-transferase 2

1

0

High-throughput

0.279

Low

907027

RABEK
Rab9 effector protein with kelch motifs

1

0

High-throughput

0.232

Low

907067

TM160
Transmembrane protein 160

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025