HitPredict

Interactor 1: PRS8 (P62195)
26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)
Gene: PSMC5

Interactor 2: K1C40 (Q6A162)
Keratin, type I cytoskeletal 40 (Cytokeratin-40) (CK-40) (Keratin-40) (K40) (Type I hair keratin Ka36)
Gene: KRT40

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	25416956, 29892012, 31515488
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 431
+	Hs
		798662 PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86		KT33B_HUMAN (23-429): 5.43e-111: 333: 58.48
+	Hs
		580008 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		K1C15_HUMAN (88-401): 4.65e-95: 295: 52.38
+	Hs
		444333 PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86		K1C19_HUMAN (82-397): 4.55e-103: 313: 51.90
+	Hs
		444327 PRS7_HUMAN (84-392): 1.21e-115: 345: 56.31		K1C19_HUMAN (82-397): 4.55e-103: 313: 51.90
+	Hs
		280967 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		KRT38_HUMAN (1-430): 8.86e-77: 247: 49.77
+	Hs
		907039 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		K1H1_HUMAN (48-425): 7.13e-75: 241: 63.23