Interactor 1: KCNQ1 (P51787)
Potassium voltage-gated channel subfamily KQT member 1 (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1) (Voltage-gated potassium channel subunit Kv7.1)
Gene: KCNQ1

Interactor 2: BACE1 (P56817)
Beta-secretase 1 (EC 3.4.23.46) (Aspartyl protease 2) (ASP2) (Asp 2) (Beta-site amyloid precursor protein cleaving enzyme 1) (Beta-site APP cleaving enzyme 1) (Memapsin-2) (Membrane-associated aspartic protease 2)
Gene: BACE1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 26454161
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005764 - lysosome
GO:0005769 - early endosome
GO:0005770 - late endosome
GO:0005886 - plasma membrane
GO:0016020 - membrane
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 676
Hs

1 501
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025