HitPredict

Interactor 1: UB2G1 (P62253)
Ubiquitin-conjugating enzyme E2 G1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G1) (E217K) (UBC7) (Ubiquitin carrier protein G1) (Ubiquitin-protein ligase G1) [Cleaved into: Ubiquitin-conjugating enzyme E2 G1, N-terminally processed]
Gene: UBE2G1

Interactor 2: RL40 (P62987)
Ubiquitin-ribosomal protein eL40 fusion protein (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40 (60S ribosomal protein L40)]
Gene: UBA52

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 170 Hs			1 128
+	Hs
		924329 UB2R2_HUMAN (1-163): 6.15e-72: 218: 54.27		RL40_HUMAN (1-128): 1.05e-56: 174: 100.00
+	Hs
		895774 UB2D3_HUMAN (5-165): 3.29e-69: 208: 32.92		RL40_HUMAN (1-128): 1.05e-56: 174: 100.00
+	Xl
		919927 UB2D2_XENLA (5-165): 1.03e-70: 212: 32.92		Q7SY79_XENLA (1-77): 3.33e-41: 145: 98.70
+	Dm
		639414 UBCD1_DROME (5-165): 3.52e-70: 210: 34.16		Q9W418_DROME (1-77): 1.45e-41: 145: 98.70
+	Hs
		924045 UB2R2_HUMAN (1-163): 6.15e-72: 218: 54.27		RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70
+	Hs
		895773 UB2D3_HUMAN (5-165): 3.29e-69: 208: 32.92		RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70
+	Hs
		475249 UB2D4_HUMAN (5-165): 1.53e-71: 213: 34.16		UBB_HUMAN (1-76): 1.52e-33: 118: 100.00
+	At
		1091932 UBC28_ARATH (5-165): 3.06e-71: 213: 32.92		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	Hs
		474984 UB2D2_HUMAN (5-165): 1.03e-70: 212: 32.92		UBB_HUMAN (1-76): 1.52e-33: 118: 100.00
+	At
		715116 UBC8_ARATH (5-165): 4.79e-71: 212: 31.68		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	At
		715132 UBC9_ARATH (5-165): 2.2e-70: 211: 31.68		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	At
		715147 UBC10_ARATH (5-165): 2.06e-70: 211: 31.06		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	At
		715157 UBC11_ARATH (5-165): 1.8e-70: 211: 32.30		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	At
		1091682 UBC7_ARATH (18-168): 1.36e-67: 204: 62.91		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	At
		1091683 UBC13_ARATH (18-168): 9e-67: 202: 63.58		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	At
		790158 UBC14_ARATH (1-168): 3.61e-66: 201: 58.93		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	Sc
		477592 UBC3_YEAST (9-166): 7.29e-36: 127: 41.62		RL40A_YEAST (1-128): 1.32e-53: 166: 89.84
+	At
		639385 UBC1_ARATH (10-164): 8.27e-31: 110: 36.77		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59
+	At
		790155 UBC2_ARATH (10-164): 7.58e-31: 110: 36.77		UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59