HitPredict

Interactor 1: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Interactor 2: MARHA (Q8NA82)
Probable E3 ubiquitin-protein ligase MARCHF10 (EC 2.3.2.27) (Membrane-associated RING finger protein 10) (Membrane-associated RING-CH protein X) (MARCH-X) (RING finger protein 190) (RING-type E3 ubiquitin transferase MARCHF10)
Gene: MARCHF10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	19549727
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Hs			1 808
+	Hs
		849338 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		MARH8_HUMAN (606-784): 2.36e-50: 180: 20.71
+	Hs
		849378 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		MARH1_HUMAN (598-784): 4.43e-50: 179: 17.86
+	Hs
		895806 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		MARH8_HUMAN (606-784): 2.36e-50: 180: 20.71
+	Hs
		919864 UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73		MARH7_HUMAN (510-798): 1.08e-37: 152: 34.62
+	Hs
		849448 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		MARH7_HUMAN (510-798): 1.08e-37: 152: 34.62
+	Hs
		895915 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		MARH7_HUMAN (510-798): 1.08e-37: 152: 34.62
+	Hs
		849469 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		MARH4_HUMAN (648-781): 1.86e-33: 135: 21.48
+	Hs
		851887 UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33		MARH7_HUMAN (510-798): 1.08e-37: 152: 34.62
+	Hs
		1199325 UB2D4_HUMAN (7-150): 2.75e-73: 218: 31.08		MARH3_HUMAN (632-764): 1.62e-32: 128: 23.31
+	Hs
		849466 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		MARH2_HUMAN (608-778): 2.77e-33: 130: 22.91
+	Hs
		919767 UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73		MARH3_HUMAN (632-764): 1.62e-32: 128: 23.31
+	Hs
		919880 UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73		MARH5_HUMAN (659-788): 1.54e-31: 126: 15.15
+	Hs
		849461 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		MARH5_HUMAN (659-788): 1.54e-31: 126: 15.15
+	Hs
		895832 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		MARH3_HUMAN (632-764): 1.62e-32: 128: 23.31
+	Hs
		895930 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		MARH5_HUMAN (659-788): 1.54e-31: 126: 15.15
+	Hs
		231862 UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73		MARH6_HUMAN (652-764): 8.25e-25: 113: 29.20
+	Hs
		1199317 UB2E2_HUMAN (5-150): 1.61e-65: 201: 27.33		MARH3_HUMAN (632-764): 1.62e-32: 128: 23.31
+	Hs
		1282354 UB2E3_HUMAN (5-150): 1.84e-65: 201: 28.00		MARH5_HUMAN (659-788): 1.54e-31: 126: 15.15
+	Hs
		851833 UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33		MARH3_HUMAN (632-764): 1.62e-32: 128: 23.31
+	Hs
		851894 UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33		MARH5_HUMAN (659-788): 1.54e-31: 126: 15.15