HitPredict

Interactor 1: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Interactor 2: MARH2 (Q9P0N8)
E3 ubiquitin-protein ligase MARCHF2 (EC 2.3.2.27) (Membrane-associated RING finger protein 2) (Membrane-associated RING-CH protein II) (MARCH-II) (RING finger protein 172) (RING-type E3 ubiquitin transferase MARCHF2)
Gene: MARCHF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	14722266
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Hs			1 246
+	Hs
		849466 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		MARH2_HUMAN (1-246): 2.21e-92: 273: 100.00
+	Hs
		1199325 UB2D4_HUMAN (7-150): 2.75e-73: 218: 31.08		MARH3_HUMAN (1-246): 2e-78: 238: 64.43
+	Hs
		919767 UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73		MARH3_HUMAN (1-246): 2e-78: 238: 64.43
+	Hs
		895832 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		MARH3_HUMAN (1-246): 2e-78: 238: 64.43
+	Hs
		1199317 UB2E2_HUMAN (5-150): 1.61e-65: 201: 27.33		MARH3_HUMAN (1-246): 2e-78: 238: 64.43
+	Hs
		851833 UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33		MARH3_HUMAN (1-246): 2e-78: 238: 64.43
+	Hs
		849378 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		MARH1_HUMAN (5-230): 1.5e-66: 209: 23.08
+	Hs
		849338 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		MARH8_HUMAN (51-239): 1.91e-60: 193: 26.53
+	Hs
		895806 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		MARH8_HUMAN (51-239): 1.91e-60: 193: 26.53
+	Hs
		231862 UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73		MARH6_HUMAN (57-245): 3.02e-48: 172: 20.67
+	Hs
		849469 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		MARH4_HUMAN (50-212): 1.28e-46: 161: 22.56
+	Hs
		919880 UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73		MARH5_HUMAN (64-235): 6.82e-32: 119: 18.04
+	Hs
		849461 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		MARH5_HUMAN (64-235): 6.82e-32: 119: 18.04
+	Hs
		895930 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		MARH5_HUMAN (64-235): 6.82e-32: 119: 18.04
+	Hs
		1282354 UB2E3_HUMAN (5-150): 1.84e-65: 201: 28.00		MARH5_HUMAN (64-235): 6.82e-32: 119: 18.04
+	Hs
		851894 UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33		MARH5_HUMAN (64-235): 6.82e-32: 119: 18.04
+	Hs
		919864 UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73		MARH7_HUMAN (64-115): 1.77e-14: 74.5: 33.87
+	Hs
		849448 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		MARH7_HUMAN (64-115): 1.77e-14: 74.5: 33.87
+	Hs
		895915 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		MARH7_HUMAN (64-115): 1.77e-14: 74.5: 33.87
+	Hs
		851887 UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33		MARH7_HUMAN (64-115): 1.77e-14: 74.5: 33.87