HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: GRB10 (Q13322)
Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Insulin receptor-binding protein Grb-IR)
Gene: GRB10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.674

Property	Details
Experiments	15722337, 35271311, 36931259
Identification Methods	pull down, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 594
+	Hs
		909481 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ITK_HUMAN (293-589): 1.9e-60: 213: 15.47
+	Hs
		411661 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		LCK_HUMAN (420-589): 7.66e-49: 179: 19.66
+	Hs
		788960 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MATK_HUMAN (454-587): 1.29e-36: 144: 26.81
+	Hs
		782766 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		CSK_HUMAN (454-587): 2.23e-26: 114: 23.19
+	Hs
		909427 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		GRB2_HUMAN (489-575): 3.64e-20: 91.4: 29.89
+	Gg
		94492 1433E_CHICK (1-255): 4.87e-154: 430: 100.00		KSYK_CHICK (485-591): 1.81e-12: 72.1: 26.17