HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: CE170 (Q5SW79)
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene: CEP170

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.671

Property	Details
Experiments	27173435, 35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1584
+	Mm
		910273 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		CE170_MOUSE (1-1584): 0: 592: 88.00
+	Hs
		910199 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		C170B_HUMAN (1-1560): 2.98e-111: 390: 28.28
+	Hs
		909915 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23
+	Hs
		909712 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		OTOG_HUMAN (184-721): 3.18e-19: 97.1: 12.04
+	Hs
		910167 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74
+	Hs
		909737 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		TICRR_HUMAN (438-1396): 4.55e-16: 86.8: 14.50
+	Hs
		909455 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ANK2_HUMAN (318-1298): 5e-14: 80.2: 13.65
+	Hs
		297821 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		K0754_HUMAN (564-1101): 7.33e-14: 79.4: 11.88