HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: RFIP1 (Q6WKZ4)
Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein)
Gene: RAB11FIP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.671

Property	Details
Experiments	35271311, 36931259, 17979178
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1283
+	Hs
		909930 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		NED4L_HUMAN (20-621): 1.55e-64: 240: 12.03
+	Mm
		910302 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		NED4L_MOUSE (20-621): 1.22e-63: 238: 12.01
+	Rn
		910358 1433E_RAT (1-255): 4.87e-154: 430: 100.00		NEDD4_RAT (20-411): 2.7e-51: 198: 13.22
+	Mm
		808343 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		NEDD4_MOUSE (20-397): 1.73e-48: 189: 14.95
+	Hs
		909736 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		RFIP2_HUMAN (12-463): 2.57e-46: 177: 34.79
+	Hs
		909981 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		RFIP5_HUMAN (1075-1278): 5.6e-39: 157: 23.87
+	Mm
		103331 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		RFIP2_MOUSE (12-463): 4.77e-39: 155: 33.92
+	Dm
		955045 1433E_DROME (1-254): 2.95e-146: 411: 82.69		Q9VWS3_DROME (14-696): 3.42e-32: 138: 17.63
+	Hs
		297821 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		K0754_HUMAN (342-935): 5.92e-16: 86: 12.86
+	Hs
		909455 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ANK2_HUMAN (161-762): 1.11e-09: 65.4: 16.59