HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: FGD6 (Q6ZV73)
FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24)
Gene: FGD6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.635

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1430
+	Hs
		909711 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		FGD5_HUMAN (9-1430): 5.62e-126: 429: 25.48
+	Hs
		164690 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MAST4_HUMAN (11-845): 1.53e-105: 374: 13.93
+	Hs
		506563 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		BCR_HUMAN (337-1239): 7.6e-102: 356: 14.44
+	Hs
		909803 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ARG28_HUMAN (310-1227): 8.64e-91: 327: 14.58
+	Hs
		910068 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ARHG4_HUMAN (598-1242): 1.09e-91: 314: 14.50
+	Mm
		910228 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		ARG28_MOUSE (409-1227): 9.88e-86: 311: 13.94
+	Hs
		909921 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SPT13_HUMAN (649-1227): 3.99e-89: 305: 14.62
+	Hs
		50576 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		PKHG3_HUMAN (810-1230): 5.16e-78: 285: 21.18
+	Hs
		909489 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ARHG5_HUMAN (640-1226): 9.96e-73: 270: 14.26