HitPredict

Interactor 1: 1433E (P62259)
14-3-3 protein epsilon (14-3-3E)
Gene: Ywhae

Interactor 2: DCLK1 (Q9JLM8)
Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)
Gene: DCLK1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16944949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001764 - neuron migration GO:0030424 - axon GO:0034504 - protein localization to nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 255 Mm			1 756
+	Hs
		166549 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		DCLK1_HUMAN (1-756): 0: 867: 96.43
+	Hs
		909811 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		DCLK2_HUMAN (1-746): 0: 781: 63.43
+	Mm
		910275 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		DCLK2_MOUSE (1-753): 0: 781: 62.13
+	Mm
		292332 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		DCX_MOUSE (6-346): 1.22e-142: 424: 72.21
+	Hs
		681770 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		AKT1_HUMAN (273-722): 1.23e-134: 408: 22.44
+	Hs
		909532 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		KCC2D_HUMAN (401-740): 5.6e-126: 387: 34.59
+	Hs
		910174 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		KCC2A_HUMAN (402-741): 2.09e-125: 384: 37.10
+	At
		965291 14332_ARATH (4-255): 1.05e-147: 414: 74.41		CDPK1_ARATH (287-716): 4.04e-127: 393: 29.87
+	At
		802001 14334_ARATH (4-255): 2.51e-145: 408: 73.62		CDPK1_ARATH (287-716): 4.04e-127: 393: 29.87
+	At
		788694 14335_ARATH (2-255): 3.04e-141: 398: 68.75		CDPK1_ARATH (287-716): 4.04e-127: 393: 29.87
+	Hs
		909590 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		KS6A2_HUMAN (397-734): 5.49e-113: 360: 25.14
+	Hs
		909531 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		KCC2G_HUMAN (403-663): 1.74e-64: 226: 44.15