HitPredict - High confidence protein-protein interactions

Interactor 1: RUXE (P62304)
Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE)
Gene: SNRPE

Interactor 2: SMD2 (P62316)
Small nuclear ribonucleoprotein Sm D2 (Sm-D2) (snRNP core protein D2)
Gene: SNRPD2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.928

Property	Details
Experiments	9417867, 35271311, 28514442, 24981860, 33961781
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000245 - spliceosomal complex assembly GO:0000387 - spliceosomal snRNP assembly GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus and 20 others more... GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex GO:0005682 - U5 snRNP GO:0005684 - U2-type spliceosomal complex GO:0005685 - U1 snRNP GO:0005686 - U2 snRNP GO:0005687 - U4 snRNP GO:0005689 - U12-type spliceosomal complex GO:0005829 - cytosol GO:0030532 - small nuclear ribonucleoprotein complex GO:0034709 - methylosome GO:0034715 - pICln-Sm protein complex GO:0034719 - SMN-Sm protein complex GO:0036261 - 7-methylguanosine cap hypermethylation GO:0046540 - U4/U6 x U5 tri-snRNP complex GO:0071005 - U2-type precatalytic spliceosome GO:0071007 - U2-type catalytic step 2 spliceosome GO:0071011 - precatalytic spliceosome GO:0071013 - catalytic step 2 spliceosome GO:1903241 - U2-type prespliceosome assembly
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	92
Hs

1	118

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Last updated: 15 Jul 2024