HitPredict

Interactor 1: JAK3 (P52333)
Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)
Gene: JAK3

Interactor 2: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (EC 3.6.1.-) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25852190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1124 Hs			1 535
+	Hs
		881838 JAK3_HUMAN (1-1124): 0: 969: 100.00		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		610584 JAK3_HUMAN (1-1124): 0: 969: 100.00		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		440697 FYN_HUMAN (815-1109): 4.95e-97: 320: 31.76		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		440187 LCK_HUMAN (799-1110): 1.35e-96: 318: 30.99		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		463055 YES_HUMAN (768-1109): 1.35e-97: 322: 29.16		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		440488 FYN_HUMAN (815-1109): 4.95e-97: 320: 31.76		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		440024 LCK_HUMAN (799-1110): 1.35e-96: 318: 30.99		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		486707 FGR_HUMAN (783-1109): 9.81e-91: 303: 29.27		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		486683 FGR_HUMAN (783-1109): 9.81e-91: 303: 29.27		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		463025 YES_HUMAN (768-1109): 1.35e-97: 322: 29.16		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		440443 FYN_HUMAN (815-1109): 4.95e-97: 320: 31.76		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		439996 LCK_HUMAN (799-1110): 1.35e-96: 318: 30.99		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		486671 FGR_HUMAN (783-1109): 9.81e-91: 303: 29.27		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		462980 YES_HUMAN (768-1109): 1.35e-97: 322: 29.16		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		440350 FYN_HUMAN (815-1109): 4.95e-97: 320: 31.76		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		440441 FYN_HUMAN (815-1109): 4.95e-97: 320: 31.76		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		439941 LCK_HUMAN (799-1110): 1.35e-96: 318: 30.99		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		439993 LCK_HUMAN (799-1110): 1.35e-96: 318: 30.99		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		486657 FGR_HUMAN (783-1109): 9.81e-91: 303: 29.27		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		486670 FGR_HUMAN (783-1109): 9.81e-91: 303: 29.27		TCPE_HUMAN (1-528): 0: 541: 32.29