HitPredict

Interactor 1: RUXG (P62308)
Small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG)
Gene: SNRPG

Interactor 2: RBM22 (Q9NW64)
Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22) (Zinc finger CCCH domain-containing protein 16)
Gene: RBM22

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0071007 - U2-type catalytic step 2 spliceosome and 1 others more... GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 76 Hs			1 420
+	Hs
		68461 RUXGL_HUMAN (1-76): 7.68e-29: 99.4: 94.74		RBM22_HUMAN (1-420): 6.25e-122: 362: 100.00
+	Hs
		911979 RUXF_HUMAN (5-73): 4.25e-24: 87.8: 24.64		RBM22_HUMAN (1-420): 6.25e-122: 362: 100.00
+	Hs
		539165 RSMB_HUMAN (1-70): 6.75e-22: 86.3: 21.25		RBM22_HUMAN (1-420): 6.25e-122: 362: 100.00
+	Sc
		746857 RUXG_YEAST (7-76): 1.94e-22: 83.4: 54.80		SLT11_YEAST (21-292): 1.39e-77: 246: 23.18
+	Sc
		746867 RUXF_YEAST (5-73): 3.07e-21: 80.5: 24.29		SLT11_YEAST (21-292): 1.39e-77: 246: 23.18
+	At
		1323436 Q9FI15_ARATH (1-70): 5.23e-22: 86.7: 22.89		RB45B_ARATH (218-341): 1.08e-27: 115: 26.61
+	Sc
		770321 RUXG_YEAST (7-76): 1.94e-22: 83.4: 54.80		NAM8_YEAST (221-305): 1.19e-19: 93: 34.12
+	Sc
		873651 RUXF_YEAST (5-73): 3.07e-21: 80.5: 24.29		NAM8_YEAST (221-305): 1.19e-19: 93: 34.12
+	Hs
		165438 RUXG_HUMAN (1-76): 1.78e-29: 100: 100.00		SR140_HUMAN (227-354): 8.9e-13: 72.2: 22.63
+	Sp
		252595 RUXG_SCHPO (1-76): 1.27e-24: 89: 47.37		CWC2_SCHPO (139-318): 8.87e-14: 74.5: 22.28
+	Sp
		223540 RUXF_SCHPO (5-72): 1.97e-23: 85.9: 23.53		CWC2_SCHPO (139-318): 8.87e-14: 74.5: 22.28
+	Hs
		165437 RUXF_HUMAN (5-73): 4.25e-24: 87.8: 24.64		SR140_HUMAN (227-354): 8.9e-13: 72.2: 22.63
+	Sc
		376834 LSM1_YEAST (9-74): 1.16e-21: 84: 30.99		PABP_YEAST (221-316): 1.12e-13: 74.8: 20.59
+	Hs
		165387 RSMB_HUMAN (1-70): 6.75e-22: 86.3: 21.25		SR140_HUMAN (227-354): 8.9e-13: 72.2: 22.63
+	Sc
		376892 RUXF_YEAST (5-73): 3.07e-21: 80.5: 24.29		PABP_YEAST (221-316): 1.12e-13: 74.8: 20.59
+	Mm
		646096 RSMB_MOUSE (1-70): 8.68e-22: 85.9: 21.25		TIA1_MOUSE (226-316): 1.54e-11: 67.5: 23.16
+	Sc
		376893 LSM3_YEAST (4-72): 2.35e-10: 53: 28.57		PABP_YEAST (221-316): 1.12e-13: 74.8: 20.59